Research &amp; Innovation / en Microfluidic device reveals how tumour shapes can predict cancer aggressiveness /news/microfluidic-device-reveals-how-tumour-shapes-can-predict-cancer-aggressiveness <span class="field field--name-title field--type-string field--label-hidden">Microfluidic device reveals how tumour shapes can predict cancer aggressiveness</span> <div class="field field--name-field-featured-picture field--type-image field--label-hidden field__item"> <img loading="eager" srcset="/sites/default/files/styles/news_banner_370/public/2024-12/Edmond-Young-%26-Sina-Kheir-cropi.jpg?h=81d682ee&amp;itok=jC4WuMgt 370w, /sites/default/files/styles/news_banner_740/public/2024-12/Edmond-Young-%26-Sina-Kheir-cropi.jpg?h=81d682ee&amp;itok=cctu1y-w 740w, /sites/default/files/styles/news_banner_1110/public/2024-12/Edmond-Young-%26-Sina-Kheir-cropi.jpg?h=81d682ee&amp;itok=acKK5d6Z 1110w" sizes="(min-width:1200px) 1110px, (max-width: 1199px) 80vw, (max-width: 767px) 90vw, (max-width: 575px) 95vw" width="740" height="494" src="/sites/default/files/styles/news_banner_370/public/2024-12/Edmond-Young-%26-Sina-Kheir-cropi.jpg?h=81d682ee&amp;itok=jC4WuMgt" alt="&quot;&quot;"> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span>rahul.kalvapalle</span></span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2024-12-18T10:46:03-05:00" title="Wednesday, December 18, 2024 - 10:46" class="datetime">Wed, 12/18/2024 - 10:46</time> </span> <div class="clearfix text-formatted field field--name-field-cutline-long field--type-text-long field--label-above"> <div class="field__label">Cutline</div> <div class="field__item"><p><em>Associate Professor Edmond Young of 91Թ's Faculty of Applied Science &amp; Engineering (left) and PhD alum Sina Kheiri co-developed the Recoverable-Spheroid-on-a-Chip with Unrestricted External Shape – or "ReSCUE" – platform (photos courtesy of Edmond Young and Sina Kheiri)</em></p> </div> </div> <div class="field field--name-field-author-reporters field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/taxonomy/term/6738" hreflang="en">Safa Jinje</a></div> </div> <div class="field field--name-field-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__item"><a href="/news/topics/breaking-research" hreflang="en">Breaking Research</a></div> </div> <div class="field field--name-field-story-tags field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/news/tags/department-mechanical-and-industrial-engineering" hreflang="en">department of mechanical and industrial engineering</a></div> <div class="field__item"><a href="/news/tags/institute-biomedical-engineering" hreflang="en">Institute of Biomedical Engineering</a></div> <div class="field__item"><a href="/news/tags/faculty-applied-science-engineering" hreflang="en">Faculty of Applied Science &amp; Engineering</a></div> </div> <div class="field field--name-field-subheadline field--type-string-long field--label-above"> <div class="field__label">Subheadline</div> <div class="field__item">The platform, developed by 91Թ researchers, allows for unprecedented control and manipulation of tumour shapes</div> </div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>Researchers in the 91Թ’s Faculty of Applied Science &amp; Engineering have designed a microfluidic platform that can be used to predict cancer cell behaviour and aggressiveness, opening up new avenues for personalized and targeted cancer treatment.</p> <p>The Recoverable-Spheroid-on-a-Chip with Unrestricted External Shape (ReSCUE) platform, developed by a team led by&nbsp;<strong>Edmond Young</strong>, an associate professor in the department of mechanical and industrial engineering, gives researchers the ability to recover and release tumoroids – tumour cells derived from patients – to perform downstream analysis and characterization.</p> <p>This allows for unprecedented control and manipulation of tumour shapes, a largely unexplored area in cancer research.</p> <p>“While there are several platforms for&nbsp;in vitro&nbsp;modelling of spheroids – three-dimensional aggregates of cells that can mimic tissues and mini tumours – a challenge in the cancer research field has been the inability to control the shape, recovery and location of these cancer organoids,”&nbsp;says&nbsp;<strong>Sina Kheiri</strong>, a PhD alum and co-lead author of the&nbsp;study, which was <a href="https://onlinelibrary.wiley.com/doi/full/10.1002/adma.202410547">published in<em>&nbsp;Advanced Materials</em></a>.&nbsp;</p> <p>“So, researchers end up with these tumours-on-a-chip that can’t be easily characterized because they are stuck on the device and can only be observed through optical microscopy.”&nbsp;&nbsp;</p> <div class="align-center"> <div class="field field--name-field-media-oembed-video field--type-string field--label-hidden field__item"><iframe src="/media/oembed?url=https%3A//youtu.be/SrrYWXGMI58&amp;max_width=0&amp;max_height=0&amp;hash=Zh9_PKbMBHVZGh20NjmpW0d1V-qrym58h2gVNie9Uz4" width="200" height="113" class="media-oembed-content" loading="eager" title="91Թ:"></iframe> </div> </div> <p>&nbsp;</p> <p>The platform also enables researchers to grow cancer organoids in different shapes. This is important, Kheiri says, because much of the current research on cancer cell&nbsp;in vitro&nbsp;modelling is focused on&nbsp;spherical tumours, but tumours in a body can take many different shapes.&nbsp;</p> <p>“In many invasive cancers, the tumour shape is not spherical. For example,&nbsp;in a recent study of 85 patients with breast cancer, only 20 per cent of tumours were spherical,” he says.&nbsp;“If modelling studies are limited to spherical tumour shapes, then we are not looking at the full parametric space and scale of tumours that are seen in real life. We are only looking at a small portion of the whole answer to understand cancer cell behaviour.”&nbsp;&nbsp;</p> <p>Kheiri’s PhD research was co-supervised by Young and <strong>Eugenia Kumacheva</strong>, a professor in the Faculty of Arts &amp; Science’s department of chemistry who is cross-appointed to the Institute of Biomedical Engineering. Kumacheva’s lab developed a biomimetic hydrogel that is used as a scaffold in the multi-layer ReSCUE platform, allowing the patient-derived cancer cells to grow and organize the way they would&nbsp;inside human tissue.&nbsp;</p> <p>The platform was developed in collaboration with <strong>David Cescon</strong>, a clinician scientist and breast medical oncologist at Princess Margaret Cancer Centre and associate professor in the Institute of Medical Science at the Temerty Faculty of Medicine. Cescon’s team provided access to the cancer cells that were used to form breast cancer organoids.&nbsp;&nbsp;&nbsp;</p> <figure role="group" class="caption caption-drupal-media align-center"> <div> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/styles/scale_image_750_width_/public/2024-12/ReSCUE%20device%20research%20image.jpg?itok=htVp78UG" width="750" height="887" alt="&quot;&quot;" class="image-style-scale-image-750-width-"> </div> </div> <figcaption><em>This image shows culture, release and transfer of tumoroids from the ReSCUE platform, as well as the released breast cancer disk-, rod-, and U-shaped tumoroids cultured in biomimetic hydrogel&nbsp;over zero, seven, 14 and 21 days (image courtesy of Young Lab)&nbsp;</em></figcaption> </figure> <p>The idea that&nbsp;tumour shapes determine cancer cell behaviour was a serendipitous discovery for Kheiri: while optimizing and developing the microfluidic platform, he discovered that some of the patient-derived tumoroids were forming positive curvatures because of the shape of the microwell. &nbsp;&nbsp;</p> <p>“I was playing with the aspect ratio of the microwells and observed that when the wells had a more rod-like or elongated shape, rather than a circular or disc shape, the tissues formed cellular strands at the regions with positive curvature,” he says. “I didn’t see that in tumoroids from the same cancer-cell sample that formed a spherical shape.</p> <p>"So, we started to&nbsp;make different shapes and analyze the effects of shape or curvature on cancer behaviour."&nbsp;&nbsp;</p> <p>The team looked at disk-, rod- and U-shaped tumoroids; they found higher cell activity and higher proliferation at the positive curvatures – where the tumour shape is convex and outward curving.&nbsp;&nbsp;</p> <p>This could mean that the growth of cells in these areas is more invasive compared to areas of the tumour that have a flat curvature.&nbsp;&nbsp;&nbsp;</p> <p>“Understanding&nbsp;the relationship between tumour shape and cell behaviour is important for predicting tumour aggressiveness and planning appropriate treatment strategies, such as targeted radiation therapy or drug delivery,” says Kheiri.&nbsp;“We want to open this door and give researchers a platform that they can use to study how different tumour shapes respond in anti-cancer drug treatment, in radiotherapy and chemotherapy.”&nbsp;&nbsp;</p> <p>Now a postdoctoral researcher&nbsp;at the Massachusetts Institute of Technology (MIT), Kheiri continues to&nbsp;provide support to the Young lab on development of the ReSCUE platform. The researchers recently submitted a U.S. patent and are looking to build on their results.&nbsp;&nbsp;</p> <p>“We hope that these uniquely shaped mini tumours can help biologists and cancer researchers better understand the biology of cancer cells and how they respond to drugs,” says Young.&nbsp;&nbsp;</p> <p>“We’re going to add even more complex features, such as surrounding vasculature. The more control we have over the features we can include in our models, the more realistic they become, and the more accurate our drug testing will be.”&nbsp;</p> </div> <div class="field field--name-field-news-home-page-banner field--type-boolean field--label-above"> <div class="field__label">News home page banner</div> <div class="field__item">Off</div> </div> Wed, 18 Dec 2024 15:46:03 +0000 rahul.kalvapalle 310862 at In photos: Geoffrey Hinton’s Nobel week in Sweden — and at 91Թ /news/photos-geoffrey-hinton-s-nobel-week-sweden-and-u-t <span class="field field--name-title field--type-string field--label-hidden">In photos: Geoffrey Hinton’s Nobel week in Sweden — and at 91Թ</span> <div class="field field--name-field-featured-picture field--type-image field--label-hidden field__item"> <img loading="eager" srcset="/sites/default/files/styles/news_banner_370/public/2024-12/GettyImages-2188689140-crop.jpg?h=81d682ee&amp;itok=P3ry-_E4 370w, /sites/default/files/styles/news_banner_740/public/2024-12/GettyImages-2188689140-crop.jpg?h=81d682ee&amp;itok=M2sEIE8G 740w, /sites/default/files/styles/news_banner_1110/public/2024-12/GettyImages-2188689140-crop.jpg?h=81d682ee&amp;itok=JqIrygXS 1110w" sizes="(min-width:1200px) 1110px, (max-width: 1199px) 80vw, (max-width: 767px) 90vw, (max-width: 575px) 95vw" width="740" height="494" src="/sites/default/files/styles/news_banner_370/public/2024-12/GettyImages-2188689140-crop.jpg?h=81d682ee&amp;itok=P3ry-_E4" alt="&quot;&quot;"> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span>mattimar</span></span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2024-12-13T10:42:24-05:00" title="Friday, December 13, 2024 - 10:42" class="datetime">Fri, 12/13/2024 - 10:42</time> </span> <div class="clearfix text-formatted field field--name-field-cutline-long field--type-text-long field--label-above"> <div class="field__label">Cutline</div> <div class="field__item"><p><em>Geoffrey Hinton delivers a speech during the Nobel Prize banquet at the City Hall in Stockholm, Sweden on Dec. 10 (photo by Jonathan Nackstrand/AFP/Getty Images)</em></p> </div> </div> <div class="field field--name-field-author-reporters field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/news/authors-reporters/mariam-matti" hreflang="en">Mariam Matti</a></div> </div> <div class="field field--name-field-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__item"><a href="/news/topics/our-community" hreflang="en">Our Community</a></div> </div> <div class="field field--name-field-story-tags field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/news/tags/artificial-intelligence" hreflang="en">Artificial Intelligence</a></div> <div class="field__item"><a href="/news/tags/department-computer-science" hreflang="en">Department of Computer Science</a></div> <div class="field__item"><a href="/news/tags/faculty-arts-science" hreflang="en">Faculty of Arts &amp; Science</a></div> <div class="field__item"><a href="/news/tags/geoffrey-hinton" hreflang="en">Geoffrey Hinton</a></div> <div class="field__item"><a href="/news/tags/nobel-prize" hreflang="en">Nobel Prize</a></div> <div class="field__item"><a href="/news/tags/research-innovation" hreflang="en">Research &amp; Innovation</a></div> </div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>It was a whirlwind week for the 91Թ’s <strong>Geoffrey Hinton</strong>, who travelled to Sweden to officially accept the 2024 Nobel Prize in Physics alongside a jam-packed schedule of receptions, lectures, talks, ceremonies, banquets and media engagements.</p> <p>The 91Թ <a href="https://www.provost.utoronto.ca/awards-funding/university-professors/">University Professor</a>&nbsp;emeritus of computer science known as the “godfather of AI” received the prestigious award <a href="/news/u-t-s-geoffrey-hinton-receives-nobel-medal-diploma-stockholm-ceremony">during a formal ceremony</a> at Stockholm Concert Hall — the main event during <a href="https://www.nobelprize.org/ceremony/nobel-week-2024/" target="_blank">Nobel Week</a>, held from Dec. 6 to 12 in Stockholm and Oslo.</p> <p>He shared the honour with <strong>John J. Hopfield</strong> of Princeton University for foundational work that paved the way for today's rapid advances in artificial intelligence, which some have called “the next industrial revolution.”</p> <p>From the days leading up to the ceremony to the celebrations overseas and back home in Toronto, here are a few highlights and behind-the-scenes glimpses of a historic moment for Hinton and the rest of the&nbsp;91Թ community.&nbsp;&nbsp;</p> <hr> <figure role="group" class="caption caption-drupal-media align-center"> <div> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/styles/scale_image_750_width_/public/2024-12/IMG_2361-crop.jpg?itok=j2DirXKQ" width="750" height="500" alt="&quot;&quot;" class="image-style-scale-image-750-width-"> </div> </div> <figcaption><em>(Photo by Jennifer Cressman)</em></figcaption> </figure> <p>After arriving in Stockholm on Dec. 5, Hinton takes part in <a href="https://www.youtube.com/watch?v=lexF-CrhOrE">a panel discussion at the Royal Swedish Academy of Engineering Sciences </a>(IVA) on AI development, humanity and the future.&nbsp;He is joined by IVA fellows <strong>Kristina Höök</strong>, <strong>Anders Sandberg</strong> and <strong>Staffan Truvé</strong>, and moderator <strong>Anette Novak</strong>.</p> <figure role="group" class="caption caption-drupal-media align-center"> <div> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/styles/scale_image_750_width_/public/2024-12/Geoffrey-Hinton-signing_-01-crop.jpg?itok=ZJ3UWHFR" width="750" height="500" alt="&quot;&quot;" class="image-style-scale-image-750-width-"> </div> </div> <figcaption><em>(© Nobel Prize Outreach / Nanaka Adachi)</em></figcaption> </figure> <p>On Dec. 6, Hinton signs the guest book at the Nobel Prize Museum, where he donated an early Boltzmann machine – a chip about the size of a postage stamp that can be used to recognize elements in data.</p> <figure role="group" class="caption caption-drupal-media align-center"> <div> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/styles/scale_image_750_width_/public/2024-12/chair-signing-crop_0.jpg?itok=pEHS1ZE7" width="750" height="500" alt="&quot;&quot;" class="image-style-scale-image-750-width-"> </div> </div> <figcaption><em>(Photos by&nbsp;© Nobel Prize Outreach / Clément Morin, left, and at right, 91Թ staff)</em></figcaption> </figure> <p>Continuing a Nobel tradition dating back to the event’s 100th anniversary in 2001, Hinton signs the underside of a chair at the Nobel Prize Museum’s restaurant, joining the names of fellow laureates etched into history.</p> <figure role="group" class="caption caption-drupal-media align-center"> <div> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/styles/scale_image_750_width_/public/2024-12/crowd-photo.jpg?itok=5f8UfOlV" width="750" height="396" alt="&quot;&quot;" class="image-style-scale-image-750-width-"> </div> </div> <figcaption><em>(Photos by Jennifer Cressman)</em></figcaption> </figure> <p>During a news conference at the Royal Swedish Academy of Sciences on Dec. 7, Hinton pauses to snap a personal photo, capturing a moment of his historic week.</p> <figure role="group" class="caption caption-drupal-media align-center"> <div> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/styles/scale_image_750_width_/public/2024-12/IMG_9271-crop_0.jpg?itok=hx-XcKLz" width="750" height="500" alt="&quot;&quot;" class="image-style-scale-image-750-width-"> </div> </div> <figcaption><em>(Photo by 91Թ staff)</em></figcaption> </figure> <p>In his <a href="/news/u-t-s-geoffrey-hinton-delivers-nobel-lecture-alongside-co-laureate">Nobel Prize lecture in physics</a> on Dec. 8, Hinton talks about how decades of his fundamental research, and that of his co-laureate, paved the way for the development of artificial neural networks and machine learning.&nbsp;</p> <p>Hinton explains the significance of the Boltzmann machine, which he based on an invention of his co-laureate that was known as the Hopfield network.</p> <figure role="group" class="caption caption-drupal-media align-center"> <div> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/styles/scale_image_750_width_/public/2024-12/GettyImages-2188261611-crop_0.jpg?itok=wU-_5TXa" width="750" height="500" alt="&quot;&quot;" class="image-style-scale-image-750-width-"> </div> </div> <figcaption><em>(Photo by Pontus Lundahl/TT News Agency/AFP via Getty Images)</em></figcaption> </figure> <p>Hinton and<strong> </strong>John J. Hopfield shake hands after delivering their Nobel Prize lectures.</p> <figure role="group" class="caption caption-drupal-media align-center"> <div> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/styles/scale_image_750_width_/public/2024-12/Nobel-Minds_110012-DSC07576-crop.jpg?itok=6p677JWj" width="750" height="500" alt="&quot;&quot;" class="image-style-scale-image-750-width-"> </div> </div> <figcaption><em>&nbsp; (© Nobel Prize Outreach / Clément Morin)&nbsp;</em></figcaption> </figure> <p>Since the 1960s, the laureates have participated in a roundtable discussion for television’s <em>Nobel Minds</em>. At the taping on Dec. 9, Hinton was joined by <strong>David Baker</strong>, <strong>Demis Hassabis</strong>, <strong>Gary Ruvkun</strong>, <strong>Daron Acemoglu</strong> and <strong>James A. Robinson</strong>.&nbsp;</p> <p>The following day, <a href="/news/u-t-s-geoffrey-hinton-receives-nobel-medal-diploma-stockholm-ceremony">Hinton officially accepted his Nobel Prize in Physics</a>.</p> <figure role="group" class="caption caption-drupal-media align-center"> <div> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/styles/scale_image_750_width_/public/2024-12/P1681852-crop.jpg?itok=TTcWwjKX" width="750" height="500" alt="&quot;&quot;" class="image-style-scale-image-750-width-"> </div> </div> <figcaption>(<em>Photo by Jonas Borg)</em></figcaption> </figure> <p>Hinton poses with <strong>Ulrika Gustafsson</strong>, his Nobel attaché, prior to the formal ceremony on Dec. 10.</p> <p>The event, which was <a href="https://www.youtube.com/watch?v=6-A4dUowT4Q&amp;t=1445s&amp;ab_channel=NobelPrize">livestreamed from Stockholm Concert Hall</a>, was watched around the world.</p> <blockquote class="twitter-tweet"> <p dir="ltr" lang="en">Congratulations to Canada’s own Geoffrey Hinton — “Godfather of AI”, Professor Emeritus, and now, Nobel laureate. <a href="https://t.co/CON0AtXokq">pic.twitter.com/CON0AtXokq</a></p> — Justin Trudeau (@JustinTrudeau) <a href="https://twitter.com/JustinTrudeau/status/1866598862753784025?ref_src=twsrc%5Etfw">December 10, 2024</a></blockquote> <p>&nbsp;</p> <script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script> <figure role="group" class="caption caption-drupal-media align-center"> <div> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/styles/scale_image_750_width_/public/2024-12/watch-party2.jpg?itok=uPDMyZzJ" width="750" height="526" alt="&quot;&quot;" class="image-style-scale-image-750-width-"> </div> </div> <figcaption><em>(Photos by Diana Tyszko, Matt Hintsa,&nbsp;Sobica Vinayagamoorthy and Shauna Rempel)</em></figcaption> </figure> <p>On Dec. 10 in Toronto, 91Թ community members shared in the moment via Nobel ceremony watch parties that were held across 91Թ<span style="font-size: 1rem;">’s&nbsp;</span><span style="font-size: 1rem;">three campuses.</span></p> <figure role="group" class="caption caption-drupal-media align-center"> <div> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/styles/scale_image_750_width_/public/2024-12/Nobel-Prize-award-ceremony-06-crop.jpg?itok=elAyKJL6" width="750" height="500" alt="&quot;&quot;" class="image-style-scale-image-750-width-"> </div> </div> <figcaption><em>(© Nobel Prize Outreach / Nanaka Adachi)&nbsp;</em></figcaption> </figure> <p>Hinton receives his Nobel Prize from King<strong> Carl XVI Gustaf </strong>of Sweden during the ceremony.</p> <figure role="group" class="caption caption-drupal-media align-center"> <div> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/styles/scale_image_750_width_/public/2024-12/GettyImages-2189247595-crop.jpg?itok=981-9H94" width="750" height="500" alt="&quot;&quot;" class="image-style-scale-image-750-width-"> </div> </div> <figcaption><em>(Photo by Jonathan Nackstrand/AFP via Getty Images)</em></figcaption> </figure> <p>Hinton sits next to <strong>Anna Sjöström Douagi</strong>, acting CEO of the Nobel Foundation, during the Nobel Prize banquet on Dec. 10.</p> <p>“If the benefits of the increased productivity can be shared equally, it will be a wonderful advance for all of humanity,” Hinton told the audience, before repeating his <a href="https://www.youtube.com/watch?v=-9cW4Gcn5WY">warnings about the near- and longer-term dangers</a> posed by rapid, unfettered progress of the technology. <a href="https://www.nobelprize.org/prizes/physics/2024/hinton/speech/">See the complete text of Hinton's acceptance speech</a>.</p> </div> <div class="field field--name-field-news-home-page-banner field--type-boolean field--label-above"> <div class="field__label">News home page banner</div> <div class="field__item">Off</div> </div> Fri, 13 Dec 2024 15:42:24 +0000 mattimar 310976 at Researchers at 91Թ, partner hospitals receive $35 million in provincial support  /news/researchers-u-t-partner-hospitals-receive-35-million-provincial-support <span class="field field--name-title field--type-string field--label-hidden">Researchers at 91Թ, partner hospitals receive $35 million in provincial support&nbsp;</span> <div class="field field--name-field-featured-picture field--type-image field--label-hidden field__item"> <img loading="eager" srcset="/sites/default/files/styles/news_banner_370/public/2024-12/GettyImages-1449330889-crop.jpg?h=81d682ee&amp;itok=sbwKCn0m 370w, /sites/default/files/styles/news_banner_740/public/2024-12/GettyImages-1449330889-crop.jpg?h=81d682ee&amp;itok=QFxQAWPq 740w, /sites/default/files/styles/news_banner_1110/public/2024-12/GettyImages-1449330889-crop.jpg?h=81d682ee&amp;itok=jaarW-pD 1110w" sizes="(min-width:1200px) 1110px, (max-width: 1199px) 80vw, (max-width: 767px) 90vw, (max-width: 575px) 95vw" width="740" height="494" src="/sites/default/files/styles/news_banner_370/public/2024-12/GettyImages-1449330889-crop.jpg?h=81d682ee&amp;itok=sbwKCn0m" alt="EV cars charging in an underground lot"> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span>lanthierj</span></span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2024-12-11T13:57:47-05:00" title="Wednesday, December 11, 2024 - 13:57" class="datetime">Wed, 12/11/2024 - 13:57</time> </span> <div class="clearfix text-formatted field field--name-field-cutline-long field--type-text-long field--label-above"> <div class="field__label">Cutline</div> <div class="field__item"><p><em>The performance of lithium ion batteries that power electric vehicles, like the ones plugged into these chargers, can be degraded by temperature fluctuations – a limitation researchers at 91Թ Engineering are working to change (photo by&nbsp;koiguo/Getty Images)</em></p> </div> </div> <div class="field field--name-field-author-reporters field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/news/authors-reporters/tyler-irving" hreflang="en">Tyler Irving</a></div> </div> <div class="field field--name-field-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__item"><a href="/news/topics/our-community" hreflang="en">Our Community</a></div> </div> <div class="field field--name-field-story-tags field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/news/tags/institute-biomedical-engineering" hreflang="en">Institute of Biomedical Engineering</a></div> <div class="field__item"><a href="/news/tags/leah-cowen" hreflang="en">Leah Cowen</a></div> <div class="field__item"><a href="/news/tags/sinai-health" hreflang="en">Sinai Health</a></div> <div class="field__item"><a href="/taxonomy/term/6923" hreflang="en">Sunnybrook Health Sciences Centre</a></div> <div class="field__item"><a href="/news/tags/temerty-faculty-medicine" hreflang="en">Temerty Faculty of Medicine</a></div> <div class="field__item"><a href="/news/tags/unity-health" hreflang="en">Unity Health</a></div> <div class="field__item"><a href="/news/tags/cell-and-systems-biology" hreflang="en">Cell and Systems Biology</a></div> <div class="field__item"><a href="/news/tags/anthropology" hreflang="en">Anthropology</a></div> <div class="field__item"><a href="/news/tags/astronomy-astrophysics" hreflang="en">Astronomy &amp; Astrophysics</a></div> <div class="field__item"><a href="/news/tags/biochemistry" hreflang="en">Biochemistry</a></div> <div class="field__item"><a href="/news/tags/centre-addiction-and-mental-health" hreflang="en">Centre for Addiction and Mental Health</a></div> <div class="field__item"><a href="/news/tags/chemistry" hreflang="en">Chemistry</a></div> <div class="field__item"><a href="/news/tags/computer-science" hreflang="en">Computer Science</a></div> <div class="field__item"><a href="/news/tags/dalla-lana-school-public-health" hreflang="en">Dalla Lana School of Public Health</a></div> <div class="field__item"><a href="/news/tags/ecology-and-evolutionary-biology" hreflang="en">Ecology and Evolutionary Biology</a></div> <div class="field__item"><a href="/news/tags/faculty-applied-science-engineering" hreflang="en">Faculty of Applied Science &amp; Engineering</a></div> <div class="field__item"><a href="/news/tags/faculty-arts-science" hreflang="en">Faculty of Arts &amp; Science</a></div> <div class="field__item"><a href="/news/tags/hospital-sick-children" hreflang="en">Hospital for Sick Children</a></div> <div class="field__item"><a href="/news/tags/laboratory-medicine-and-pathobiology" hreflang="en">Laboratory Medicine and Pathobiology</a></div> <div class="field__item"><a href="/news/tags/leslie-dan-faculty-pharmacy" hreflang="en">Leslie Dan Faculty of Pharmacy</a></div> <div class="field__item"><a href="/news/tags/mathematics" hreflang="en">Mathematics</a></div> <div class="field__item"><a href="/news/tags/physics" hreflang="en">Physics</a></div> <div class="field__item"><a href="/news/tags/psychology" hreflang="en">Psychology</a></div> <div class="field__item"><a href="/news/tags/research-innovation" hreflang="en">Research &amp; Innovation</a></div> <div class="field__item"><a href="/news/tags/university-health-network" hreflang="en">University Health Network</a></div> <div class="field__item"><a href="/news/tags/utias" hreflang="en">UTIAS</a></div> </div> <div class="field field--name-field-subheadline field--type-string-long field--label-above"> <div class="field__label">Subheadline</div> <div class="field__item">From better batteries to preventing memory loss, nearly four dozen projects at 91Թ and its partner hospitals are being supported by the&nbsp;Ontario Research Fund </div> </div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>Researchers in the 91Թ’s&nbsp;Thermal Management Systems (TMS) Laboratory&nbsp;are working to improve the way battery systems handle heat and develop structural battery pack components. &nbsp;</p> <p>“Whether they are being used for electric vehicles or for stationary energy storage systems that reduce strain on the grid, lithium-ion batteries are transforming the way we use electricity,” said <strong>Carlos Da Silva</strong>, senior research associate at the TMS Lab in the Faculty of Applied Science &amp; Engineering and executive director of 91Թ’s <a href="https://electrification.utoronto.ca/">Electrification Hub</a>.&nbsp;</p> <p>“Unfortunately, today’s batteries are still sensitive to temperature: if they get too cold or too hot, it can degrade their performance and even present safety risks. We are working on new technologies that make batteries more resilient to thermal fluctuations.”&nbsp;</p> <p>The battery-related research is among nearly four dozen projects at 91Թ and its partner hospitals that are receiving almost $35 million in support through the&nbsp;<a href="https://news.ontario.ca/en/release/1005382/ontario-investing-92-million-to-support-made-in-ontario-research-and-innovation">Ontario Research Fund – Research Excellence (ORF-RE) and the Ontario Research Fund – Small Infrastructure (ORF-SIF)</a>. (<a href="#list">See the full list of projects and their principal researchers below</a>).&nbsp;</p> <p>"Research at the 91Թ and at all universities and colleges across Ontario is the foundation of the province’s competitiveness now and in the future,” said&nbsp;<strong>Leah Cowen</strong>, 91Թ’s vice-president, research and innovation, and strategic initiatives.&nbsp;&nbsp;</p> <p>“This investment protects and advances cutting-edge, made-in-Ontario research in important economic sectors and helps ensure universities can continue to train, attract and retain the world’s top talent."&nbsp;</p> <p>At 91Թ Engineering’s TMS Lab, researchers led by&nbsp;<strong>Cristina Amon</strong>, a&nbsp;<a href="https://www.provost.utoronto.ca/awards-funding/university-professors/">University Professor</a>&nbsp;in the department of mechanical and industrial engineering, are working on two funded projects. They are developing advanced computational modelling and digital twin methodologies that predict and optimize how heat flows through battery packs. The methodologies are carefully calibrated and validated through industry-relevant experiments in the lab.&nbsp;</p> <figure role="group" class="caption caption-drupal-media align-center"> <div> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/styles/scale_image_750_width_/public/2024-12/TMSlab-2--33_crop.jpg?itok=yj7xlK64" width="750" height="500" alt="&quot;&quot;" class="image-style-scale-image-750-width-"> </div> </div> <figcaption><em>Senior Research Associate Carlos Da Silva, left, and University Professor Cristina Amon, right, chat in the Faculty of Applied Science &amp; Engineering's Thermal Management Systems Laboratory (photo by Aaron Demeter)</em></figcaption> </figure> <p>These methodologies will help battery designers anticipate and prevent thermal management challenges before they arise. It can also enable them to optimize the design and deployment of fire mitigation measures, such as ultra-thin heat barriers, within their battery systems.&nbsp;</p> <p>The team is also collaborating with Ford Canada and several other companies in the energy storage space. For example, they have worked with Jule (powered by eCAMION) on the development of direct current electric vehicle fast chargers with integrated battery energy storage systems, one of which was <a href="/news/battery-powered-ev-chargers-co-developed-u-t-installed-st-george-campus">recently unveiled on the 91Թ campus</a>.&nbsp;</p> <p>“We are grateful for this ORF-RE funding, which will accelerate our research and help us further expand our partnerships, ensuring that battery thermal innovations have a seamless transition from the lab to the marketplace,” Amon said.&nbsp;</p> <p>“As a result of this work, the next generation of batteries will be safer and more resilient than ever before, which is especially important in colder climates like ours here in Ontario.” &nbsp;<a id="list" name="list"></a></p> <hr> <h4>Ontario Research Fund – Research Excellence:</h4> <ul> <li><a href="https://discover.research.utoronto.ca/13404-cristina-amon"><strong>Cristina Amon</strong></a>&nbsp;in the department of mechanical &amp; industrial engineering in the Faculty of Applied Science &amp; Engineering – <em>Powering Ontario’s grid transformation and electric vehicle fast charging with thermally resilient battery energy storage &amp; Next-gen electric vehicle battery systems: Lightweight, thermally performant and fire safe for all climates</em></li> <li><a href="https://discover.research.utoronto.ca/23353-morgan-barense"><strong>Morgan Barense</strong></a>&nbsp;in the&nbsp;department of psychology in the Faculty of Arts &amp; Science – <em>HippoCamera: Digital memory rehabilitation to combat memory loss</em></li> <li><a href="https://discover.research.utoronto.ca/21538-aimy-bazylak"><strong>Aimy Bazylak</strong></a>&nbsp;in the department of mechanical &amp; industrial engineering in the Faculty of Applied Science and Engineering – <em>RECYCLEAN: Critical minerals recycling &amp; re-manufacturing for the energy transition</em></li> <li><strong>Ian Connell</strong>&nbsp;at University Health Network and the department of medical biophysics in the Temerty Faculty of Medicine – <em>MRI-compatible innovations for neuromodulation</em></li> <li><strong>Simon Graham</strong>&nbsp;at Sunnybrook Health Sciences Centre and the department of medical biophysics in the Temerty Faculty of Medicine – <em>Technological innovations for clinical MRI of the brain at 7 tesla</em></li> <li><a href="https://discover.research.utoronto.ca/19009-clinton-groth"><strong>Clinton Groth</strong></a>&nbsp;in the Institute for Aerospace Studies in the Faculty of Applied Science &amp; Engineering – <em>Hydrogen as a sustainable aviation fuel – combustion research to remove impediments to adoption in gas turbine engines</em></li> <li><strong>James Kennedy&nbsp;</strong>at Centre for Addiction and Mental Health and the department of psychiatry in the Temerty Faculty of Medicine – <em>Clinical utility and enhancements of a pharmacogenomic decision support tool for mental health patients</em></li> <li><strong>Shaf Keshavjee</strong>&nbsp;at University Health Network and the department of surgery in the Temerty Faculty of Medicine – <em>Advanced solutions to human lung preservation and assessment using artificial intelligence</em></li> <li><strong>Aviad Levis</strong>&nbsp;in the department of computer science in the Faculty of Arts &amp; Science – <em>AI and quantum enhanced astronomy</em></li> <li><strong>JoAnne McLaurin</strong>&nbsp;at Sunnybrook Health Sciences Centre and the department of laboratory medicine &amp; pathobiology in the Temerty Faculty of Medicine – <em>Conversion of astrocytes to neurons to treat neurodegenerative diseases of the brain and the eye</em></li> <li><a href="https://discover.research.utoronto.ca/21310-r-j-dwayne-miller"><strong>R. J. Dwayne Miller</strong></a>&nbsp;in the department of chemistry in the Faculty of Arts &amp; Science – <em>PicoSecond InfraRed Laser (PIRL) “cancer knife” with complete biodiagnostics via spatial imaging mass spectrometry</em></li> <li><a href="https://discover.research.utoronto.ca/10412-javad-mostaghimi"><strong>Javad Mostaghimi</strong></a>&nbsp;in the department of mechanical &amp; industrial engineering in the Faculty of Applied Science &amp; Engineering – <em>A new generation of compact, transportable mass spectrometers for rapid, in-field sample analysi</em></li> <li><a href="https://discover.research.utoronto.ca/12421-shirley-xy-wu"><strong>Xiao Yu (Shirley) Wu</strong></a>&nbsp;in the Leslie Dan Faculty of Pharmacy – <em>Molecular dynamics modeling and screening of excipients for designing amorphous solid dispersion formulations of poorly–soluble drugs</em></li> </ul> <h4>Ontario Research Fund – Small Infrastructure Fund:</h4> <ul> <li><a href="https://discover.research.utoronto.ca/28945-celina-baines"><strong>Celina Baines</strong></a>&nbsp;in the department of ecology &amp; evolutionary biology in the Faculty of Arts &amp; Science –&nbsp;<em>Impacts of environmental change on organismal movement</em></li> <li><strong>Sergio de la Barrera</strong>&nbsp;in the department of physics in the Faculty of Arts &amp; Science –&nbsp;<em>Facility for quantum materials and device assembly from atomically thin van der Waals layers</em></li> <li><strong>Michelle Bendeck</strong>&nbsp;in the department of laboratory medicine &amp; pathobiology in the Temerty Faculty of Medicine –&nbsp;<em>4D quantitative cardiovascular physiology centre</em></li> <li><a href="https://discover.research.utoronto.ca/1070-laurent-bozec"><strong>Laurent Bozec</strong></a>&nbsp;in the department of laboratory medicine &amp; pathobiology in the Temerty Faculty of Medicine –&nbsp;<em>21st Century challenge for Dentistry: Breaking the cycle of irreversible dental tissue loss</em></li> <li><a href="https://discover.research.utoronto.ca/45747-mark-chiew"><strong>Mark Chiew</strong></a>&nbsp;at Sunnybrook Health Sciences Centre and the department of medical biophysics in the Temerty Faculty of Medicine –&nbsp;<em>Next generation computational MRI for rapid neuroimaging and image-guided therapy</em></li> <li><a href="https://discover.research.utoronto.ca/42705-haissi-cui"><strong>Haissi Cui</strong></a>&nbsp;in the department of chemistry in the Faculty of Arts &amp; Science –&nbsp;<em>A molecule to mouse approach to study the intracellular localization of genetic code interpretation in mammalian cells</em></li> <li><strong>Andy Kin On DeVeale</strong>&nbsp;at the University Health Network and the Dalla Lana School of Public Health –&nbsp;<em>Sarcopenia and musculoskeletal interactions (sami) collaborative hub</em></li> <li><strong>Ali Dolatabadi</strong>&nbsp;in the department of mechanical &amp; industrial engineering in the Faculty of Applied Science &amp; Engineering –&nbsp;<em>Advanced cold spray facility</em></li> <li><strong>Spencer Freeman</strong>&nbsp;at the Hospital for Sick Children and the department of biochemistry in the Temerty Faculty of Medicine –&nbsp;<em>Imaging biophysical determinants of the innate immune response</em></li> <li><strong>Liisa Galea</strong>&nbsp;at the Centre for Addiction and Mental Health and the Institute of Medical Science in the Temerty Faculty of Medicine –&nbsp;<em>Sex and sex-specific factors influencing brain health across the lifespan</em></li> <li><a href="https://discover.research.utoronto.ca/5658-maged-goubran"><strong>Maged Goubran</strong></a>&nbsp;at Sunnybrook Health Sciences Centre and the department of medical biophysics in the Temerty Faculty of Medicine –&nbsp;<em>AI platform for mapping, tracking and predicting circuit alterations in Alzheimer’s disease</em></li> <li><strong>Eitan Grinspun</strong>&nbsp;in the departments of computer science and department of mathematics in the Faculty of Arts &amp; Science –&nbsp;<em>A computer graphics perspective on entanglement of slender structures</em></li> <li><strong>Levon Halabelian</strong>&nbsp;in the Department of Pharmacology and Toxicology in the Temerty Faculty of Medicine –&nbsp;<em>Enabling a high-throughput drug discovery pipeline for targeting disease-related human proteins</em></li> <li><strong>Ziqing Hong</strong>&nbsp;in the department of physics in the Faculty of Arts &amp; Science –&nbsp;<em>Ultra-sensitive cryogenic detector development for dark matter and neutrino experiments&nbsp;</em></li> <li><strong>Eno Hysi</strong>&nbsp;at the Unity Health Toronto and the department of medical biophysics in the Temerty Faculty of Medicine –&nbsp;<em>Structural and functional assessments of diabetic skin microvasculature using photoacoustic imaging</em></li> <li><a href="https://discover.research.utoronto.ca/6634-lewis-kay"><strong>Lewis Kay</strong></a>&nbsp;in the department of biochemistry in the Temerty Faculty of Medicine – <em>Helium recovery system for the biomolecular NMR facility</em></li> <li><strong>Xiang Li&nbsp;</strong>in the department of chemistry and the department of physic in the Faculty of Arts &amp; Science –&nbsp;<em>Real-time multi-faceted probes of quantum materials</em></li> <li><strong>Qian Lin</strong>&nbsp;in the department of cell &amp; systems biology in the Faculty of Arts &amp; Science –&nbsp;<em>2p-RAM for whole-brain single-neuron imaging of behaving zebrafish to study neural mechanisms of cognitive behaviours</em></li> <li><a href="https://discover.research.utoronto.ca/34676-xilin-liu"><strong>Xilin Liu</strong></a>&nbsp;in the Edward S. Rogers Sr. department of electrical and computer engineering in the Faculty of Applied Science &amp; Engineering –&nbsp;<em>Integrated circuits for wireless brain implants with multi-modal neural interfaces</em></li> <li><strong>Stephen Lye</strong>&nbsp;at the Sinai Health System and the department of physiology in the Temerty Faculty of Medicine –&nbsp;<em>Healthy Life Trajectories Initiative (HeLTI) analytics platform</em></li> <li><a href="https://discover.research.utoronto.ca/52975-caitlin-maikawa"><strong>Caitlin Maikawa</strong></a>&nbsp;in the Institute of Biomedical Engineering in the Faculty of Applied Science &amp; Engineering –&nbsp;<em>Biointerfacing&nbsp;materials for drug delivery lab</em></li> <li><a href="https://discover.research.utoronto.ca/6448-emma-master"><strong>Emma Master</strong></a>&nbsp;in the department of chemical engineering &amp; applied chemistry in the Faculty of Applied Science &amp; Engineering –&nbsp;<em>Accelerating biomanufacturing innovation through enhanced capacity for scale-up and downstream bioprocess engineering</em></li> <li><strong>Roman Melnyk</strong>&nbsp;at the Hospital for Sick Children and the department of biochemistry in the Temerty Faculty of Medicine –&nbsp;<em>The H-SCREEN: A platform for high throughput and high content imaging-based small molecule screens for disease modulation</em></li> <li><strong>Juan Mena-Parra</strong>&nbsp;in the department of astronomy &amp; astrophysics in the Faculty of Arts &amp; Science –&nbsp;<em>An advanced laboratory to enable novel radio telescopes for cosmology and time-domain astrophysics</em></li> <li><strong>Seyed Mohamad Moosavi</strong>&nbsp;in the department of chemical engineering and applied chemistry in the Faculty of Applied Science &amp; Engineering –<em>&nbsp;Machine learning for nanoporous materials design</em></li> <li><strong>Enid Montague</strong>&nbsp;in the department of mechanical &amp; industrial engineering in the Faculty of Applied Science &amp; Engineering –&nbsp;<em>Automation and equity in healthcare laboratory</em></li> <li><strong>Michael Norris</strong>&nbsp;in the department of biochemistry in the Temerty Faculty of Medicine –&nbsp;<em>Infrastructure for structural and functional virology research hub</em></li> <li><a href="https://discover.research.utoronto.ca/18432-amaya-perezbrumer"><strong>Amaya Perez-Brumer</strong></a>&nbsp;in the Dalla Lana School of Public Health –&nbsp;<em>3P lab: Centering power, privilege and positionality for health equity research</em></li> <li><strong>Monica Ramsey</strong>&nbsp;in the department of anthropology at the 91Թ Mississauga –&nbsp;<em>Ramsey Laboratory for Environmental Archaeology (RLEA): How human-environment interactions shaped plant-food</em></li> <li><strong>Arneet Saltzman</strong>&nbsp;in the department of cell &amp; systems biology in the in the Faculty of Arts &amp; Science –&nbsp;<em>Heterochromatin regulation in development and inheritance</em></li> <li><a href="https://discover.research.utoronto.ca/13279-mina-tadrous"><strong>Mina Tadrous</strong></a>&nbsp;in the Leslie Dan Faculty of Pharmacy –&nbsp;<em>Developing a centre for real-world evidence to improve the use of medications for Canadians</em></li> <li><a href="https://discover.research.utoronto.ca/25515-shurui-zhou"><strong>Shurui Zhou</strong></a>&nbsp;in the department of electrical &amp; computer engineering in the Faculty of Applied Science &amp; Engineering –&nbsp;<em>Improving collaboration efficiency for fork-based software development</em></li> <li><strong>Olena Zhulyn</strong>&nbsp;at the Hospital for Sick Children and the department of molecular genetics in the Temerty Faculty of Medicine –&nbsp;<em>Targeting translation for tissue regeneration and repair</em></li> <li><strong>Christoph Zrenner</strong>&nbsp;at the Centre for Addiction and Mental Health and the Institute of Biomedical Engineering in the Faculty of Applied Science &amp; Engineering –&nbsp;<em>Next-generation real-time closed-loop personalized neurostimulation</em></li> </ul> </div> <div class="field field--name-field-news-home-page-banner field--type-boolean field--label-above"> <div class="field__label">News home page banner</div> <div class="field__item">Off</div> </div> Wed, 11 Dec 2024 18:57:47 +0000 lanthierj 310908 at 91Թ’s Geoffrey Hinton receives Nobel medal, diploma at Stockholm ceremony /news/u-t-s-geoffrey-hinton-receives-nobel-medal-diploma-stockholm-ceremony <span class="field field--name-title field--type-string field--label-hidden">91Թ’s Geoffrey Hinton receives Nobel medal, diploma at Stockholm ceremony</span> <div class="field field--name-field-featured-picture field--type-image field--label-hidden field__item"> <img loading="eager" srcset="/sites/default/files/styles/news_banner_370/public/2024-12/GettyImages-2188637863-crop.jpg?h=9c7d8071&amp;itok=dGMYIMUZ 370w, /sites/default/files/styles/news_banner_740/public/2024-12/GettyImages-2188637863-crop.jpg?h=9c7d8071&amp;itok=rTeYMuIV 740w, /sites/default/files/styles/news_banner_1110/public/2024-12/GettyImages-2188637863-crop.jpg?h=9c7d8071&amp;itok=hS2D5SZe 1110w" sizes="(min-width:1200px) 1110px, (max-width: 1199px) 80vw, (max-width: 767px) 90vw, (max-width: 575px) 95vw" width="740" height="494" src="/sites/default/files/styles/news_banner_370/public/2024-12/GettyImages-2188637863-crop.jpg?h=9c7d8071&amp;itok=dGMYIMUZ" alt="&quot;&quot;"> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span>Christopher.Sorensen</span></span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2024-12-10T15:05:05-05:00" title="Tuesday, December 10, 2024 - 15:05" class="datetime">Tue, 12/10/2024 - 15:05</time> </span> <div class="clearfix text-formatted field field--name-field-cutline-long field--type-text-long field--label-above"> <div class="field__label">Cutline</div> <div class="field__item"><p><em>91Թ University Professor Emeritus&nbsp;Geoffrey Hinton receives his Nobel Prize in Physics from King Carl XVI Gustaf of Sweden during the Nobel Prize award ceremony in Stockholm (photo by Henrik Montgomery/TT News Agency/AFP/Getty Images)&nbsp;</em></p> </div> </div> <div class="field field--name-field-author-reporters field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/news/authors-reporters/rahul-kalvapalle" hreflang="en">Rahul Kalvapalle</a></div> </div> <div class="field field--name-field-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__item"><a href="/news/topics/global-lens" hreflang="en">Global Lens</a></div> </div> <div class="field field--name-field-story-tags field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/news/tags/artificial-intelligence" hreflang="en">Artificial Intelligence</a></div> <div class="field__item"><a href="/news/tags/computer-science" hreflang="en">Computer Science</a></div> <div class="field__item"><a href="/news/tags/faculty-arts-science" hreflang="en">Faculty of Arts &amp; Science</a></div> <div class="field__item"><a href="/news/tags/geoffrey-hinton" hreflang="en">Geoffrey Hinton</a></div> <div class="field__item"><a href="/news/tags/nobel-prize" hreflang="en">Nobel Prize</a></div> </div> <div class="field field--name-field-subheadline field--type-string-long field--label-above"> <div class="field__label">Subheadline</div> <div class="field__item">“I think we all feel an enormous amount of pride in the fact that [91Թ] is one of the places where modern machine learning was really born - in large part due to Geoff Hinton”</div> </div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>The 91Թ’s&nbsp;<strong>Geoffrey Hinton</strong>&nbsp;officially accepted <a href="/news/geoffrey-hinton-wins-nobel-prize">his Nobel Prize in Physics</a> during a formal ceremony at Stockholm Concert Hall that included orchestra music, an opera singer and a stage lined with bouquets of flowers.&nbsp;</p> <p>Wearing white tie and tails, Hinton strode across the dark blue stage emblazoned with the words “The Nobel Prize” to receive his Nobel medal and diploma from King <strong>Carl XVI Gustaf </strong>of Sweden. Then, as the Royal Stockholm Philharmonic Orchestra sounded a few triumphant notes, he bowed to the Swedish royal family, the audience and returned to his seat at the side of the stage.</p> <figure role="group" class="caption caption-drupal-media align-center"> <div> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/styles/scale_image_750_width_/public/2024-12/GettyImages-2188634106-crop.jpg?itok=8J4z0C6T" width="750" height="500" alt="&quot;&quot;" class="image-style-scale-image-750-width-"> </div> </div> <figcaption><em>Geoffrey Hinton looks out over the audience after King Carl XVI Gustaf of Sweden presented him with his award (photo by Henrik Montgomery/TT News Agency/AFP/Getty Images)</em></figcaption> </figure> <p>And just like that, decades of scholarly endeavour in artificial intelligence (AI) – which began on the fringe of the AI research community and is now poised to forever change modern life – culminated in the 91Թ&nbsp;<a href="https://www.provost.utoronto.ca/awards-funding/university-professors/">University Professor</a> emeritus of computer science known as the “godfather of AI” receiving humanity’s most prestigious award for scientific achievement.</p> <p>Hinton shared the 2024 Nobel Prize in Physics with<strong>&nbsp;John J. Hopfield</strong>&nbsp;of Princeton University, who made a similar journey inside the concert hall a few moments earlier. The pair were awarded the prize for discoveries and inventions that enabled machine learning with artificial neural networks, laying the groundwork for today’s AI boom.&nbsp;</p> <div class="align-center"> <div class="field field--name-field-media-oembed-video field--type-string field--label-hidden field__item"><iframe src="/media/oembed?url=https%3A//www.youtube.com/live/6-A4dUowT4Q%3Fsi%3D5xmElbezCHq6hcmo&amp;max_width=0&amp;max_height=0&amp;hash=aaXjqkKa4Y3Z1eQD2H2OR0mzQIm49Enlg11OBGFLNA4" width="200" height="113" class="media-oembed-content" loading="eager" title="2024 Nobel Prize award ceremony"></iframe> </div> </div> <p>&nbsp;</p> <p>“[Geoffrey Hinton] pioneered the efforts to establish deep and dense neural networks,” said&nbsp;<strong>Ellen Moons</strong>,&nbsp;the chair of the Nobel physics committee, during her introductory remarks. “Such networks are effective in sorting and interpreting large amounts of data and self-improve based on the accuracy of the result.</p> <p>&nbsp;“Today, artificial neural networks are powerful tools in research fields spanning physics, chemistry and medicine, as well as in daily life.”</p> <p>In fact, the three winners of the 2024 Nobel Prize in Chemistry – who were seated to Hinton’s left – drew heavily on AI for their work in predicting protein structures and computational design of proteins.&nbsp;</p> <figure role="group" class="caption caption-drupal-media align-center"> <div> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/styles/scale_image_750_width_/public/2024-12/Image-%282%29-1-crop.jpg?itok=hDCYMZOq" width="750" height="500" alt="&quot;&quot;" class="image-style-scale-image-750-width-"> </div> </div> <figcaption><em>91Թ President Meric Gertler snapped this photo of the Nobel laureates from his seat in the concert hall (photo by Meric Gertler)</em></figcaption> </figure> <p>Back in Toronto, members of the 91Թ community gathered at watch parties on all three campuses to take in the livestream of the awards ceremony – a historic moment for the university.&nbsp;</p> <p>On the St. George campus, more than one hundred gathered to watch and cheer in the main lobby of the Schwartz Reisman Innovation Campus – home to 91Թ’s&nbsp;<a href="https://srinstitute.utoronto.ca/">Schwartz Reisman Institute for Technology and Society</a>&nbsp;and the&nbsp;<a href="https://vectorinstitute.ai/">Vector Institute for Artificial Intelligence</a>, where Hinton serves as an advisory board member and chief scientific adviser, respectively.&nbsp;</p> <p>Among the gathered audience was&nbsp;<strong>Michael Guerzhoy</strong>,&nbsp;an assistant professor, teaching stream, of engineering science and mechanical and industrial engineering in the Faculty of Applied Science &amp; Engineering who took Hinton’s course on neural networks and machine learning in 2005 – before going on to teach the same course himself several years later.&nbsp;</p> <p>“I think we all feel an enormous amount of pride in the fact that this is one of the places where modern machine learning was really born, in large part due to Geoff Hinton,” Guerzhoy said. “I think a lot of us owe a personal debt of gratitude to him.”</p> <figure role="group" class="caption caption-drupal-media align-center"> <div> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/styles/scale_image_750_width_/public/2024-12/20241210_Hinton-Nobel-UTSG-Watch-Party_48-crop.jpg?itok=2u71dFIL" width="750" height="500" alt="&quot;&quot;" class="image-style-scale-image-750-width-"> </div> </div> <figcaption><em>91Թ community members gather in the lobby of the Schwartz Reisman Innovation Campus to watch the ceremony (photo by Matt Hintsa)</em></figcaption> </figure> <p>Fourth-year undergraduate student&nbsp;<strong>James Wang</strong>&nbsp;said he was “in awe” as he watched Hinton receive his Nobel Prize.&nbsp;</p> <p>“It makes you feel inspired. You want to be like him, you want to attain the highest level of achievement that anybody can achieve – and not just to do it for your sake, but also for the academic community at large,” Wang said.&nbsp;</p> <p>There were similar expressions of pride and jubilation at 91Թ Mississauga, where community members congregated to watch the livestream in the atrium of the Communication Culture &amp; Technology Building, and at 91Թ Scarborough, where a watch party was organized in the Meeting Place.&nbsp;</p> <p>As per tradition, the awarding of the Nobel Prize medal and diploma took place on Dec. 10, the anniversary of the death of&nbsp;<strong>Alfred Nobel</strong>&nbsp;who, in his 1885 will, bequeathed his fortune to create the award.</p> <figure role="group" class="caption caption-drupal-media align-center"> <div> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/styles/scale_image_750_width_/public/2024-12/IMG_0058-crop-UTSC.jpg?itok=LXCV9nuz" width="750" height="500" alt="&quot;&quot;" class="image-style-scale-image-750-width-"> </div> </div> <figcaption><em>Attendees at 91Թ Scarborough's Nobel watch party hold up signs (photo by&nbsp;Sobica Vinayagamoorthy)</em></figcaption> </figure> <p>The gold medal for the Nobel Prize in Physics depicts nature in the form of a goddess resembling Isis, her face covered by a veil held up by the Genius of Science. Inscribed are the Latin words, “<em>Inventas vitam iuvat excoluisse per artes</em>,”which are translated to: “It is beneficial to have improved (human) life through discovered arts.”&nbsp;</p> <p>The Nobel diploma is crafted on handmade paper and bound in a dark blue leather cover.&nbsp;</p> <figure role="group" class="caption caption-drupal-media align-center"> <div> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/styles/scale_image_750_width_/public/2024-12/DL_NOBEL_diplom_0019_W.jpg?itok=r58P2PMv" width="750" height="500" alt="&quot;&quot;" class="image-style-scale-image-750-width-"> </div> </div> <figcaption><em>The Nobel Prize diploma features a unique work of art, with the design decided by the prize-awarding bodies (© Nobel Prize Outreach. Photo: Dan Lepp Artist: Lars Eje Larsson Calligrapher: Marie A. Györi Book binder: Leonard Gustafssons Bokbinderi AB )</em></figcaption> </figure> <p>Later in the evening, Hinton joined his fellow Nobel laureates, their families, friends and dignitaries for a banquet at Stockholm City Hall.&nbsp;</p> <p>In an interview with Swedish national broadcaster SVT on the sidelines of the event, Hinton said it was “very exciting but also very exhausting” to take part in the day’s Nobel events.&nbsp;</p> <p>Reflecting on his upbringing and career, Hinton said his school years – raised as an atheist who went to a Christian school – helped prepare him for his early years as a cognitive scientist working in the then-peripheral area of artificial intelligence.&nbsp;</p> <p>“From a young age, I was surrounded at school, everybody else had a different opinion and I thought they were wrong – that was very useful when I was studying neural nets,” Hinton said.</p> <p>“For many, many years, there were only a few of us who believed in neural nets. Everybody else said this was a ridiculous thing to study. And it turned out we were right.”</p> <p><em>– with files from Adam Elliot Segal</em></p> </div> <div class="field field--name-field-news-home-page-banner field--type-boolean field--label-above"> <div class="field__label">News home page banner</div> <div class="field__item">Off</div> </div> Tue, 10 Dec 2024 20:05:05 +0000 Christopher.Sorensen 310967 at 91Թ ranked world’s most sustainable university for second year in a row /news/u-t-ranked-world-s-most-sustainable-university-second-year-row <span class="field field--name-title field--type-string field--label-hidden">91Թ ranked world’s most sustainable university for second year in a row</span> <div class="field field--name-field-featured-picture field--type-image field--label-hidden field__item"> <img loading="eager" srcset="/sites/default/files/styles/news_banner_370/public/2024-12/UofT88694_0U1A1809-copy-crop.jpg?h=aed5a58a&amp;itok=7g5RJxhv 370w, /sites/default/files/styles/news_banner_740/public/2024-12/UofT88694_0U1A1809-copy-crop.jpg?h=aed5a58a&amp;itok=771hKOiz 740w, /sites/default/files/styles/news_banner_1110/public/2024-12/UofT88694_0U1A1809-copy-crop.jpg?h=aed5a58a&amp;itok=9nLZL20_ 1110w" sizes="(min-width:1200px) 1110px, (max-width: 1199px) 80vw, (max-width: 767px) 90vw, (max-width: 575px) 95vw" width="740" height="494" src="/sites/default/files/styles/news_banner_370/public/2024-12/UofT88694_0U1A1809-copy-crop.jpg?h=aed5a58a&amp;itok=7g5RJxhv" alt="researcher tends to a rooftop garden at UTSC"> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span>Christopher.Sorensen</span></span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2024-12-10T11:12:41-05:00" title="Tuesday, December 10, 2024 - 11:12" class="datetime">Tue, 12/10/2024 - 11:12</time> </span> <div class="clearfix text-formatted field field--name-field-cutline-long field--type-text-long field--label-above"> <div class="field__label">Cutline</div> <div class="field__item"><p><em>(photo by Don Campbell)</em></p> </div> </div> <div class="field field--name-field-author-reporters field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/news/authors-reporters/rahul-kalvapalle" hreflang="en">Rahul Kalvapalle</a></div> </div> <div class="field field--name-field-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__item"><a href="/news/topics/global-lens" hreflang="en">Global Lens</a></div> </div> <div class="field field--name-field-story-tags field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/news/tags/climate-positive-campus" hreflang="en">Climate Positive Campus</a></div> <div class="field__item"><a href="/news/tags/climate-positive-energy" hreflang="en">Climate Positive Energy</a></div> <div class="field__item"><a href="/news/tags/institutional-strategic-initiatives" hreflang="en">Institutional Strategic Initiatives</a></div> <div class="field__item"><a href="/news/tags/sustainable-development-goals" hreflang="en">Sustainable Development Goals</a></div> <div class="field__item"><a href="/news/tags/global" hreflang="en">Global</a></div> <div class="field__item"><a href="/news/tags/meric-gertler" hreflang="en">Meric Gertler</a></div> <div class="field__item"><a href="/news/tags/qs-world-university-rankings" hreflang="en">QS World University Rankings</a></div> <div class="field__item"><a href="/news/tags/rankings" hreflang="en">Rankings</a></div> <div class="field__item"><a href="/news/tags/st-george" hreflang="en">St. George</a></div> <div class="field__item"><a href="/news/tags/sustainability" hreflang="en">Sustainability</a></div> <div class="field__item"><a href="/news/tags/u-t-mississauga" hreflang="en">91Թ Mississauga</a></div> <div class="field__item"><a href="/news/tags/u-t-scarborough" hreflang="en">91Թ Scarborough</a></div> </div> <div class="field field--name-field-subheadline field--type-string-long field--label-above"> <div class="field__label">Subheadline</div> <div class="field__item">The 2025 edition of the QS World University Rankings: Sustainability ranked 91Թ first out of more than 1,700 institutions across 95 countries&nbsp;</div> </div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>The 91Թ has been ranked the most sustainable university in the world for the second consecutive year.&nbsp;</p> <p>The <a href="https://www.topuniversities.com/sustainability-rankings">2025 edition of the QS World University Rankings: Sustainability</a>, released this week by London-based Quacquarelli Symonds, placed 91Թ first overall out of more than 1,700 institutions across 95 countries.&nbsp;</p> <p>The closely watched ranking evaluates post-secondary institutions for their environmental impact, social impact and governance.</p> <p>“On behalf of the 91Թ, I am thrilled that our university is once again ranked first in the world in the QS Sustainability Rankings,” said 91Թ President&nbsp;<strong>Meric Gertler</strong>. “The 91Թ community is profoundly committed to the advancement of sustainability as one of the most urgent challenges of our time.&nbsp;</p> <p>“This year’s ranking confirms our resolve to help lead the way to a sustainable future.”</p> <div class="align-center"> <div class="field field--name-field-media-oembed-video field--type-string field--label-hidden field__item"><iframe src="/media/oembed?url=https%3A//youtu.be/zBD62oKbcKI&amp;max_width=0&amp;max_height=0&amp;hash=rLgNpgmKUO5SUSODfk7oJkKvQYGu9lCgV6sn6jfQ1u8" width="200" height="113" class="media-oembed-content" loading="eager" title="91Թ ranked world’s most sustainable university for second year in a row"></iframe> </div> </div> <p><a href="/news/u-t-ranked-2nd-world-first-ever-qs-sustainability-ranking">First launched in 2022</a>, the ranking assesses universities based on&nbsp;<a href="/news/u-t-ranked-second-among-north-american-public-universities-among-top-25-globally-qs-world">QS World University Rankings</a>&nbsp;data, including reputation surveys and research output related to the&nbsp;<a href="https://sdgs.un.org/goals">17 UN Sustainable Development Goals</a>. It also looks at institutional policies, operational data, alumni impact and national data from the Organisation for Economic Co-operation and Development (OECD) and World Bank.</p> <p>To determine environmental impact, the ranking evaluates environmental education, research and sustainability. For social impact, it examines&nbsp;<a href="/news/u-t-among-top-15-universities-globally-graduate-employability-times-higher-education">employability and outcomes</a>, equality, health and well-being, impact of education and knowledge exchange. And for governance, the ranking looks at indicators such as student representation and transparent financial reporting.&nbsp;</p> <p>91Թ performed particularly well in the social impact category this year, moving up three spots to first globally. It also ranked fifth in the world for environmental impact and tied for 23<sup>rd</sup>&nbsp;<a href="/news/how-u-t-s-secret-sauce-governance-model-set-it-five-decades-success">in governance</a>.</p> <p>91Թ’s performance led a robust showing by Canadian universities. The University of British Columbia shared fifth spot with University College London, making Canada the only country to have two universities in the top five. Two other Canadian universities placed in the top 50: McGill University (15<sup>th</sup>) and Western University (30<sup>th</sup>).</p> <p>The QS sustainability ranking comes as 91Թ forges ahead with a host of climate-focused initiatives on its own campuses including:&nbsp;<a href="/news/u-t-cut-carbon-emissions-half-st-george-campus-2027">Project Leap</a>, a $138-million infrastructure project that will cut emissions on the St. George campus in half by 2027;&nbsp;<a href="https://www.utm.utoronto.ca/green/home/climate-positive/distribute#:~:text=Utilities%20Plant%20Tunnel-,Project%20SHIFT,-Dubbed%20Project%20SHIFT">Project SHIFT</a>, a 91Թ Mississauga initiative to speed up the transition from natural gas to electricity; and a combination of new climate-responsible constructions and energy retrofits to older buildings at 91Թ Scarborough.</p> <p>Spurred by these and other efforts, the university’s three campuses last year made <a href="/news/u-t-s-plan-become-climate-positive-expanded-all-three-campuses">a&nbsp;landmark commitment</a>&nbsp;to reduce more greenhouse gases than they emit in the coming years. And 91Թ continues to make progress on&nbsp;its <a href="/news/u-t-divest-fossil-fuel-investments-create-climate-positive-campus">pledge to divest from fossil fuel investments&nbsp;in its endowment fund</a>.</p> <p>At the same time, 91Թ is working to enhance Canada’s green energy sector through projects like the&nbsp;<a href="https://cpe.utoronto.ca/grid-modernization-centre/">Grid Modernization Centre</a>, a state-of-the-art facility led by&nbsp;<a href="https://cpe.utoronto.ca/">Climate Positive Energy</a>, an&nbsp;<a href="https://isi.utoronto.ca/">institutional strategic initiative</a>,&nbsp;that will serve as a hub for testing, development and commercialization.</p> <p>91Թ is also playing a leadership role in sustainability by engaging with regional, national and international partners. For example, the university acted as a founding member of the City of Toronto’s&nbsp;<a href="https://www.toronto.ca/services-payments/water-environment/net-zero-homes-buildings/better-buildings-partnership/green-will-initiative/">Green Will Initiative</a>, collaborated with the&nbsp;<a href="https://urbanclimateactionproject.ca/">Urban Climate Action Project</a>&nbsp;to help implement the city’s&nbsp;<a href="https://www.toronto.ca/services-payments/water-environment/environmentally-friendly-city-initiatives/transformto/">TransformTO</a>&nbsp;climate action strategy and contributed to the Toronto Region Board of Trade’s&nbsp;<a href="https://bot.com/Resources/Resource-Library/Banking-on-Green-Playbook"><em>Banking on Green</em></a>&nbsp;playbook, which helps Ontario organizations fund green retrofit projects.</p> <p>Globally, 91Թ has convened networks aimed at mobilizing multi-sector partnerships, including the U7+ Alliance of World Universities, the University Climate Change Coalition (UC3) and the International Sustainable Campus Network (ISCN). 91Թ’s sustainability leaders have also been asked to share knowledge and experiences with other universities in Canada, the U.S., Mexico, Germany and other countries.</p> <p>Most important, 91Թ is actively creating a new generation of sustainability leaders. Supported by the&nbsp;<a href="https://sustainability.utoronto.ca/ceccs-home/">President’s Advisory Committee on the Environment, Climate Change, and Sustainability (CECCS)</a>, which recently created a new&nbsp;<a href="https://sustainability.utoronto.ca/ceccs-subcommittees/student-leadership-subcommittee/">student leadership subcommittee</a>, more than 2,000 undergraduate courses in 2024-25 now&nbsp;have <a href="https://sustainability.utoronto.ca/resources/inventories/sustainability-course-inventory/">a sustainability orientation</a>.&nbsp;</p> <p>Students also have the option of exploring sustainability from various lenses through the&nbsp;<a href="https://sustainability.utoronto.ca/ceccs-subcommittees/teaching-and-learning/sustainability-pathways-program/#:~:text=U%20of%20T%20Sustainability%20Pathways,%2C%20methodological%2C%20and%20practical%20perspectives.">Sustainability Pathways program</a>, or to contribute to projects on- and off-campus via the&nbsp;<a href="https://sustainability.utoronto.ca/ceccs-subcommittees/operations/campus-as-a-living-lab/">Campus as a Living Lab</a>&nbsp;and&nbsp;<a href="https://experientiallearning.utoronto.ca/learningtype/community-engaged-learning/">Community-Engaged Learning&nbsp;programs</a>.</p> <p>Overall, 91Թ continues to be the highest-ranked Canadian university and one of the top-ranked public universities in the five most closely watched international rankings:&nbsp;<em>Times Higher Education’s</em>&nbsp;World University Rankings, QS World University Rankings, ShanghaiRanking Consultancy’s Academic Ranking of World Universities,&nbsp;<em>U.S. News &amp; World Report’s</em>&nbsp;Best Global Universities and National Taiwan University World University Rankings.</p> </div> <div class="field field--name-field-news-home-page-banner field--type-boolean field--label-above"> <div class="field__label">News home page banner</div> <div class="field__item">On</div> </div> Tue, 10 Dec 2024 16:12:41 +0000 Christopher.Sorensen 310934 at 91Թ’s Geoffrey Hinton delivers Nobel lecture alongside co-laureate  /news/u-t-s-geoffrey-hinton-delivers-nobel-lecture-alongside-co-laureate <span class="field field--name-title field--type-string field--label-hidden">91Թ’s Geoffrey Hinton delivers Nobel lecture alongside co-laureate&nbsp;</span> <div class="field field--name-field-featured-picture field--type-image field--label-hidden field__item"> <img loading="eager" srcset="/sites/default/files/styles/news_banner_370/public/2024-12/GettyImages-2188261611-crop.jpg?h=cc175432&amp;itok=icBiWQY6 370w, /sites/default/files/styles/news_banner_740/public/2024-12/GettyImages-2188261611-crop.jpg?h=cc175432&amp;itok=4P4Pq_y- 740w, /sites/default/files/styles/news_banner_1110/public/2024-12/GettyImages-2188261611-crop.jpg?h=cc175432&amp;itok=lUsz1tOy 1110w" sizes="(min-width:1200px) 1110px, (max-width: 1199px) 80vw, (max-width: 767px) 90vw, (max-width: 575px) 95vw" width="740" height="494" src="/sites/default/files/styles/news_banner_370/public/2024-12/GettyImages-2188261611-crop.jpg?h=cc175432&amp;itok=icBiWQY6" alt="&quot;&quot;"> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span>Christopher.Sorensen</span></span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2024-12-09T15:48:27-05:00" title="Monday, December 9, 2024 - 15:48" class="datetime">Mon, 12/09/2024 - 15:48</time> </span> <div class="clearfix text-formatted field field--name-field-cutline-long field--type-text-long field--label-above"> <div class="field__label">Cutline</div> <div class="field__item"><p><em>91Թ's Geoffrey Hinton, left, and John J. Hopfield of Princeton University, right, who share the 2024 Nobel Prize in Physics, shake hands after their Nobel lectures in Stockholm (photo by Pontus Lundahl/TT News Agency/AFP via Getty Images)</em></p> </div> </div> <div class="field field--name-field-author-reporters field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/news/authors-reporters/rahul-kalvapalle" hreflang="en">Rahul Kalvapalle</a></div> </div> <div class="field field--name-field-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__item"><a href="/news/topics/global-lens" hreflang="en">Global Lens</a></div> </div> <div class="field field--name-field-story-tags field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/news/tags/leah-cowen" hreflang="en">Leah Cowen</a></div> <div class="field__item"><a href="/news/tags/schwartz-reisman-institute-technology-and-society" hreflang="en">Schwartz Reisman Institute for Technology and Society</a></div> <div class="field__item"><a href="/news/tags/artificial-intelligence" hreflang="en">Artificial Intelligence</a></div> <div class="field__item"><a href="/news/tags/computer-science" hreflang="en">Computer Science</a></div> <div class="field__item"><a href="/news/tags/faculty-applied-science-engineering" hreflang="en">Faculty of Applied Science &amp; Engineering</a></div> <div class="field__item"><a href="/news/tags/faculty-arts-science" hreflang="en">Faculty of Arts &amp; Science</a></div> <div class="field__item"><a href="/news/tags/geoffrey-hinton" hreflang="en">Geoffrey Hinton</a></div> <div class="field__item"><a href="/news/tags/meric-gertler" hreflang="en">Meric Gertler</a></div> <div class="field__item"><a href="/news/tags/nobel-prize" hreflang="en">Nobel Prize</a></div> <div class="field__item"><a href="/news/tags/vector-institute" hreflang="en">Vector Institute</a></div> </div> <div class="field field--name-field-subheadline field--type-string-long field--label-above"> <div class="field__label">Subheadline</div> <div class="field__item">In Stockholm for a series of Nobel Week events, the “godfather of AI” will officially accept his Nobel Prize in Physics at a ceremony on Dec. 10</div> </div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>The 91Թ’s&nbsp;<strong>Geoffrey Hinton</strong>&nbsp;took to the stage at the Swedish Academy in Stockholm this weekend – two days before he officially accepts&nbsp;<a href="/news/geoffrey-hinton-wins-nobel-prize">his Nobel Prize in Physics</a>&nbsp;for fundamental work in AI – to deliver a lecture on the inventions and discoveries that led to him being given the prestigious award.</p> <p>“Today, I’m going to do something very foolish – I’m going to try and describe a complicated technical idea for a general audience, without using any equations,” said Hinton, a 91Թ&nbsp;<a href="https://www.provost.utoronto.ca/awards-funding/university-professors/#section_1">University Professor&nbsp;</a>emeritus of computer science, prompting laughter from the audience.&nbsp;</p> <p>The “godfather of AI” then proceeded to outline how decades of his fundamental research, and that of his co-laureate&nbsp;<strong>John J. Hopfield</strong>&nbsp;of Princeton University, enabled the development of artificial neural networks and machine learning – technologies that underpin today’s AI revolution.</p> <p>The Nobel lectures are among the highlights of&nbsp;<a href="https://www.nobelprize.org/ceremony/nobel-week-2024/">Nobel Week</a>, which runs from Dec. 6-12 in Stockholm and Oslo and includes award ceremonies, banquets, media engagements and commemorations at the Nobel Museum.&nbsp;There is also <a href="/utogether/nobel-week-u-of-t-2024">a series of&nbsp;Nobel Week events taking place at 91Թ</a>, including watch parties on all three campuses for the livestream of the Dec. 10 award ceremony.&nbsp;</p> <div> <div class="field field--name-field-media-oembed-video field--type-string field--label-hidden field__item"><iframe src="/media/oembed?url=https%3A//www.youtube.com/live/lPIVl5eBPh8%3Fsi%3Di-SoYWQm6TlBWk7T&amp;max_width=0&amp;max_height=0&amp;hash=OlLO0toiuR2wjq5AeIpQ3f9VeutmG2JeBriZNPc0k_M" width="200" height="113" class="media-oembed-content" loading="eager" title="2024 Nobel Prize lectures in physics | John Hopfield and Geoffrey Hinton"></iframe> </div> </div> <p>&nbsp;</p> <p>Sunday’s first Nobel Prize lecture in physics was delivered by Hopfield, who shared how his fascination with the workings of the human brain inspired his development of the Hopfield network – an associative memory that can store and reconstruct patterns in data.&nbsp;</p> <p>“How mind emerges from brain is, to me, the deepest question posed by our humanity,” Hopfield said.</p> <p>When it was Hinton’s turn to take the stage, he described how he and&nbsp;<strong>Terry Sejnowski</strong>&nbsp;– one of Hopfield’s students – came upon a novel use of Hopfield nets: “Instead of using them to store memories, we could use them to construct interpretations of sensory input,” Hinton said.</p> <p>He then went on to discuss the resulting Boltzmann machine, a type of neural network that is capable of recognizing elements within data.&nbsp;</p> <figure role="group" class="caption caption-drupal-media align-center"> <div> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/styles/scale_image_750_width_/public/2024-12/IMG_9271-crop.jpg?itok=_xYXFhpd" width="750" height="500" alt="&quot;&quot;" class="image-style-scale-image-750-width-"> </div> </div> <figcaption><em>Hinton discusses the significance of the Boltzmann machine (photo by 91Թ staff)</em></figcaption> </figure> <p>Yet, despite its promise, the original Boltzmann machine was too slow, Hinton said, and it wasn’t until several years later that he came up with “restricted Boltzmann machines,” which impose limitations on connections between neurons in order to increase system efficiency – a development that would prove pivotal in training deep neural networks (Hinton donated an early Boltzmann chip, about the size of a postage stamp, to the Nobel Prize Museum).&nbsp;</p> <p>Following the lecture, Hinton was joined on stage by Hopfield, with the pair sharing a vigorous handshake and posing for photos.</p> <figure role="group" class="caption caption-drupal-media align-center"> <div> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/styles/scale_image_750_width_/public/2024-12/P1671273-.jpgcrop.jpg?itok=wtvNueDM" width="750" height="500" alt="&quot;&quot;" class="image-style-scale-image-750-width-"> </div> </div> <figcaption><em>91Թ brought together a panel of experts in Stockholm to discuss AI research and development (photo by Jonas Borg)</em></figcaption> </figure> <p>Separately, 91Թ convened an expert panel in Stockholm on Monday about the direction of AI research and development.</p> <p>Moderated by&nbsp;<strong>Leah Cowen</strong>, 91Թ’s vice-president, research and innovation, and strategic initiatives, the panel included:&nbsp;<strong>Eyal de Lara</strong>, a professor and chair of the department of computer science in 91Թ’s Faculty of Arts &amp; Science;&nbsp;<strong>David Lie</strong>, director of the&nbsp;<a href="https://srinstitute.utoronto.ca/">Schwartz Reisman Institute for Technology and Society</a> and a professor in the Edward S. Rogers Sr. department of electrical and computer engineering in the Faculty of Applied Science &amp; Engineering;&nbsp;<strong>Tony Gaffney</strong>, president and CEO of the&nbsp;<a href="https://vectorinstitute.ai/">Vector Institute for Artificial Intelligence</a>; and&nbsp;<strong>Amy Loutfi</strong>, professor of computer science and pro-vice-chancellor for AI at Örebro University in Sweden.</p> <p>The conversation touched on areas including the promising applications of AI, how responsible deployment of AI can mitigate the technology’s potential pitfalls and implications of AI’s rise on education.</p> <p>91Թ President&nbsp;<strong>Meric Gertler</strong>&nbsp;said that the AI breakthroughs fostered by Hinton’s research were made possible by Canada’s longstanding support of basic research.</p> <p>&nbsp;“Geoff was interested in the novel but unproven concept of artificial neural networks, an area that was sometimes described as the ‘unpromising backwater’ of AI research,” President Gertler said in his remarks introducing the panel, noting that Hinton joined 91Թ in 1987 and was one of the first scholars to receive support from the&nbsp;<a href="https://cifar.ca/">Canadian Institute for Advanced Research</a>&nbsp;(CIFAR).</p> <p>“Canada was investing in brilliant people, their ideas and their students – and those investments have paid off many years later.”</p> <p>Canada was also the first country to launch a national AI roadmap, President Gertler said, in the form of the Pan-Canadian Artificial Intelligence Strategy – which funds three national AI institutes including the Vector Institute for Artificial Intelligence, which is now housed in 91Թ’s new Schwartz Reisman Innovation Campus. The state-of-the-art building also hosts the Schwartz Reisman Institute for Technology and Society, which is at the forefront of research and thought leadership on AI safety and responsible development, with Hinton one of its advisory board members.</p> <p>“In short, Canada has played a key role in launching and driving the AI revolution and we’re a world leader in understanding and promoting safe, human-centred AI,” President Gertler said.&nbsp;</p> <p>The theme of responsible AI was also brought up during&nbsp;a Q-and-A with Hinton, who revealed that the remarkable information-sharing abilities of large language models played a big role in sparking his now oft-repeated concerns around the current pace of the technology’s development.&nbsp;</p> <p>“That’s when I came to realize that the fact that they’re so much better at sharing probably means that digital intelligence is just a better form of intelligence than us – and that’s what got me so worried,” he said.&nbsp;</p> <p>Asked what responsible AI regulation looks like, Hinton said there must first be a consensus around solving the problem from a scientific standpoint – not unlike the scientific consensus that has emerged around climate change.</p> <p>“Like the early days of climate change, the first thing to do is figure out what’s causing it and get scientific agreement on how you can fix it. Then, the second thing to do is get the politicians to do something about it … but here, we haven’t finished the first thing yet.”&nbsp;</p> <p>&nbsp;</p> </div> <div class="field field--name-field-news-home-page-banner field--type-boolean field--label-above"> <div class="field__label">News home page banner</div> <div class="field__item">Off</div> </div> Mon, 09 Dec 2024 20:48:27 +0000 Christopher.Sorensen 310957 at Geoffrey Hinton shares 2024 VinFuture Grand Prize for work on deep learning /news/geoffrey-hinton-shares-2024-vinfuture-grand-prize-work-deep-learning <span class="field field--name-title field--type-string field--label-hidden">Geoffrey Hinton shares 2024 VinFuture Grand Prize for work on deep learning</span> <div class="field field--name-field-featured-picture field--type-image field--label-hidden field__item"> <img loading="eager" srcset="/sites/default/files/styles/news_banner_370/public/2024-12/UofT96529_2024-10-24-Hinton-FitzGerald-Building-%289%29-smaller-crop.jpg?h=9c94f4e7&amp;itok=LKA4Gyq0 370w, /sites/default/files/styles/news_banner_740/public/2024-12/UofT96529_2024-10-24-Hinton-FitzGerald-Building-%289%29-smaller-crop.jpg?h=9c94f4e7&amp;itok=jYoVrKat 740w, /sites/default/files/styles/news_banner_1110/public/2024-12/UofT96529_2024-10-24-Hinton-FitzGerald-Building-%289%29-smaller-crop.jpg?h=9c94f4e7&amp;itok=KB0a2GpX 1110w" sizes="(min-width:1200px) 1110px, (max-width: 1199px) 80vw, (max-width: 767px) 90vw, (max-width: 575px) 95vw" width="740" height="494" src="/sites/default/files/styles/news_banner_370/public/2024-12/UofT96529_2024-10-24-Hinton-FitzGerald-Building-%289%29-smaller-crop.jpg?h=9c94f4e7&amp;itok=LKA4Gyq0" alt="&quot;&quot;"> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span>Christopher.Sorensen</span></span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2024-12-06T14:32:41-05:00" title="Friday, December 6, 2024 - 14:32" class="datetime">Fri, 12/06/2024 - 14:32</time> </span> <div class="clearfix text-formatted field field--name-field-cutline-long field--type-text-long field--label-above"> <div class="field__label">Cutline</div> <div class="field__item"><p><em>(photo by Johnny Guatto)</em></p> </div> </div> <div class="field field--name-field-author-reporters field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/news/authors-reporters/rahul-kalvapalle" hreflang="en">Rahul Kalvapalle</a></div> </div> <div class="field field--name-field-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__item"><a href="/news/topics/global-lens" hreflang="en">Global Lens</a></div> </div> <div class="field field--name-field-story-tags field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/news/tags/leah-cowen" hreflang="en">Leah Cowen</a></div> <div class="field__item"><a href="/news/tags/schwartz-reisman-institute-technology-and-society" hreflang="en">Schwartz Reisman Institute for Technology and Society</a></div> <div class="field__item"><a href="/news/tags/artificial-intelligence" hreflang="en">Artificial Intelligence</a></div> <div class="field__item"><a href="/news/tags/awards" hreflang="en">Awards</a></div> <div class="field__item"><a href="/news/tags/computer-science" hreflang="en">Computer Science</a></div> <div class="field__item"><a href="/news/tags/faculty-arts-science" hreflang="en">Faculty of Arts &amp; Science</a></div> <div class="field__item"><a href="/news/tags/geoffrey-hinton" hreflang="en">Geoffrey Hinton</a></div> <div class="field__item"><a href="/news/tags/research-innovation" hreflang="en">Research &amp; Innovation</a></div> <div class="field__item"><a href="/news/tags/vector-institute" hreflang="en">Vector Institute</a></div> </div> <div class="field field--name-field-subheadline field--type-string-long field--label-above"> <div class="field__label">Subheadline</div> <div class="field__item">Known as the "godfather of AI," Hinton was one of five people honoured with the US$3-million prize awarded by Vietnam's VinFuture Foundation</div> </div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p><strong>Geoffrey Hinton</strong>,&nbsp;<a href="http://www.provost.utoronto.ca/awards-funding/university-professors/">University Professor</a>&nbsp;emeritus of computer science at the 91Թ and <a href="/news/geoffrey-hinton-wins-nobel-prize">winner of the 2024 Nobel Prize in Physics</a>, has added another prestigious award to his collection:&nbsp;<a href="https://www.accesswire.com/951373/the-2024-vinfuture-prize-honors-four-scientific-works-under-the-theme-of-resilient-rebound">the 2024 VinFuture Grand Prize</a>.</p> <p>The US$3-million prize, awarded by the not-for-profit&nbsp;<a href="https://vinfutureprize.org/">VinFuture Foundation</a>&nbsp;in Vietnam, recognizes seminal scientific advancements that are improving the quality of human life and forging a more equitable and sustainable world.</p> <p>Hinton, known as the “godfather of AI,” shares the prize with&nbsp;<strong>Yoshua Bengio</strong>,&nbsp;<strong>Jen-Hsun (Jensen) Huang</strong>,&nbsp;<strong>Yann LeCun</strong>&nbsp;and&nbsp;<strong>Fei-Fei Li</strong>. The five are honoured for their contributions to the development and adoption of deep learning, which is revolutionizing fields ranging from biomedical research and transportation to manufacturing, clean energy and agriculture.</p> <p>“The 91Թ couldn’t be more proud of University Professor Emeritus Geoff Hinton,” said&nbsp;<strong>Leah Cowen</strong>, 91Թ’s vice-president, research and innovation, and strategic initiatives. “When Geoff arrived at 91Թ nearly 40 years ago, his research into neural networks – influenced by his ideas about how the brain learns – was considered an AI backwater, if it was considered at all.&nbsp;</p> <p>“Fast-forward to today, and his seminal work is transforming our world in ways that we’ve only begun to grasp. This award is a testament to the power of curiosity-driven research – and the impact of investing in brilliant, curious researchers.”</p> <p>The VinFuture Foundation noted that Hinton and Bengio – a professor at the Université de Montréal – were awarded the prize for their research on neural networks and deep learning algorithms. LeCun, the chief AI scientist for Facebook AI Research who was one of Hinton’s post-doctoral students at 91Թ in the1980s, was recognized for helping develop convolutional neural networks for computer vision. Huang, the co-founder and CEO of NVIDIA, was recognized for his work on computational architectures for deep learning and accelerated computing, while Li, a professor at Stanford University, was celebrated for contributions to computer vision and large-scale image recognition.</p> <p>In a video message, Hinton, an adviser at 91Թ’s&nbsp;<a href="https://srinstitute.utoronto.ca/">Schwartz Reisman Institute for Technology and Society</a>&nbsp;who is also co-founder and chief scientific adviser at the&nbsp;<a href="https://vectorinstitute.ai/">Vector Institute for Artificial Intelligence</a>&nbsp;in Toronto, said he was honoured to share the award with such an esteemed group of researchers – including his fellow&nbsp;<a href="/news/am-turing-award-nobel-prize-computing-given-hinton-and-two-other-ai-pioneers">A.M Turing Award-winners</a>&nbsp;Bengio and LeCun.</p> <p>“The three of us spent our whole lives developing the technology of neural networks,” Hinton said in remarks that noted the collective nature of the achievement.</p> <p>“I’m very happy to see that the VinFuture Prize recognizes the contributions of Jensen Huang in developing the kind of compute and software required for artificial intelligence,&nbsp;<a href="/news/geoffrey-hinton-and-fei-fei-li-draw-thousands-talk-about-responsible-ai-development">and Fei-Fei Li</a>&nbsp;in providing the big data that was needed to prove that it worked.”</p> <p>Now in its fourth year, the VinFuture Prize was created with the goal of celebrating scientific and technological innovations that are aligned with the <a href="https://sdgs.un.org/goals">United Nations’ 17 Sustainable Development Goals</a>, which include poverty alleviation, renewable energy, ending hunger and improving health.</p> <p>Friday’s award ceremony was attended by Vietnam’s Prime Minister&nbsp;<strong>Pham Minh Chinh</strong>&nbsp;and distinguished leaders, scientists and diplomats from around the world. It was broadcast live on Vietnamese television and&nbsp;streamed online.&nbsp;</p> <p>“It’s terrific to see this recognition of Geoff’s extraordinary work and its potential to help address some of the world’s greatest challenges,” said&nbsp;Cowen. “Researchers around the globe – including a number of his former students – are using AI to help solve some of the most pressing challenges of our time in areas such as health care, sustainability and climate change.”</p> <p>The prize comes as Hinton&nbsp;<a href="/news/his-public-stature-grows-godfather-ai-geoffrey-hinton-heads-stockholm-accept-his-nobel-prize">prepares to officially accept his Nobel Prize in Physics in Sweden</a>&nbsp;on Dec. 10. He shared the Nobel with&nbsp;<strong>John J. Hopfield</strong>&nbsp;of Princeton University for foundational discoveries and inventions that enable machine learning with artificial neural networks.</p> <p>Hinton, who joined 91Թ in 1987 after working in universities in the U.K. and U.S., has said that he plans to leverage his growing fame to&nbsp;<a href="https://www.youtube.com/watch?v=-9cW4Gcn5WY">spread awareness of the dangers of unchecked AI development</a>&nbsp;– a warning he first shared after leaving a research position at Google in early 2023.</p> </div> <div class="field field--name-field-news-home-page-banner field--type-boolean field--label-above"> <div class="field__label">News home page banner</div> <div class="field__item">Off</div> </div> Fri, 06 Dec 2024 19:32:41 +0000 Christopher.Sorensen 310935 at As his public stature grows, ‘Godfather of AI’ Geoffrey Hinton heads to Stockholm to accept his Nobel Prize  /news/his-public-stature-grows-godfather-ai-geoffrey-hinton-heads-stockholm-accept-his-nobel-prize <span class="field field--name-title field--type-string field--label-hidden">As his public stature grows, ‘Godfather of AI’ Geoffrey Hinton heads to Stockholm to accept his Nobel Prize&nbsp;</span> <div class="field field--name-field-featured-picture field--type-image field--label-hidden field__item"> <img loading="eager" srcset="/sites/default/files/styles/news_banner_370/public/2024-12/UofT96523_2024-10-24-Hinton-FitzGerald-Building-%283%29-smalle-cropr.jpg?h=43a10973&amp;itok=W2Lz-Ava 370w, /sites/default/files/styles/news_banner_740/public/2024-12/UofT96523_2024-10-24-Hinton-FitzGerald-Building-%283%29-smalle-cropr.jpg?h=43a10973&amp;itok=3DtxgTyI 740w, /sites/default/files/styles/news_banner_1110/public/2024-12/UofT96523_2024-10-24-Hinton-FitzGerald-Building-%283%29-smalle-cropr.jpg?h=43a10973&amp;itok=kqgXPbr2 1110w" sizes="(min-width:1200px) 1110px, (max-width: 1199px) 80vw, (max-width: 767px) 90vw, (max-width: 575px) 95vw" width="740" height="494" src="/sites/default/files/styles/news_banner_370/public/2024-12/UofT96523_2024-10-24-Hinton-FitzGerald-Building-%283%29-smalle-cropr.jpg?h=43a10973&amp;itok=W2Lz-Ava" alt="&quot;&quot;"> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span>lanthierj</span></span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2024-12-04T12:56:55-05:00" title="Wednesday, December 4, 2024 - 12:56" class="datetime">Wed, 12/04/2024 - 12:56</time> </span> <div class="clearfix text-formatted field field--name-field-cutline-long field--type-text-long field--label-above"> <div class="field__label">Cutline</div> <div class="field__item"><p>University Professor Emeritus Geoffrey Hinton will receive the 2024 Nobel Prize in Physics on Dec. 10 (photo by Johnny Guatto)</p> </div> </div> <div class="field field--name-field-author-reporters field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/news/authors-reporters/chris-sorensen" hreflang="en">Chris Sorensen</a></div> </div> <div class="field field--name-field-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__item"><a href="/news/topics/our-community" hreflang="en">Our Community</a></div> </div> <div class="field field--name-field-story-tags field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/news/tags/artificial-intelligence" hreflang="en">Artificial Intelligence</a></div> <div class="field__item"><a href="/news/tags/department-computer-science" hreflang="en">Department of Computer Science</a></div> <div class="field__item"><a href="/news/tags/faculty-arts-science" hreflang="en">Faculty of Arts &amp; Science</a></div> <div class="field__item"><a href="/news/tags/geoffrey-hinton" hreflang="en">Geoffrey Hinton</a></div> <div class="field__item"><a href="/news/tags/nobel-prize" hreflang="en">Nobel Prize</a></div> <div class="field__item"><a href="/news/tags/research-innovation" hreflang="en">Research &amp; Innovation</a></div> </div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>“Godfather of AI” <strong>Geoffrey Hinton</strong> was already on his way to becoming a household name when he won the 2024 Nobel Prize in Physics for foundational work leading to today’s artificial intelligence boom.&nbsp;&nbsp;</p> <p>Two months later, his celebrity has hit a whole new level.&nbsp;</p> <p>The <a href="https://www.provost.utoronto.ca/awards-funding/university-professors/">University Professor</a> emeritus at the 91Թ says he now gets recognized on the street and that strangers regularly ask him for selfies. On a recent flight to Toronto, one flight attendant even grabbed the intercom to announce his presence on the plane. That’s in addition to a torrent of requests to speak to media, appear on podcasts and read academic papers.&nbsp;</p> <p>As he prepares to travel to Stockholm on Dec. 10 to officially accept the honour alongside co-winner <strong>John J. Hopfield</strong> of Princeton University – which will be celebrated via <a href="/utogether/nobel-week-u-of-t-2024">watch parties and other “Nobel Week” events at 91Թ</a>&nbsp;– Hinton says he plans to put his growing fame to good use.&nbsp;</p> <div class="align-center"> <div class="field field--name-field-media-oembed-video field--type-string field--label-hidden field__item"><iframe src="/media/oembed?url=https%3A//youtu.be/5hQ-KCEQUE8&amp;max_width=0&amp;max_height=0&amp;hash=UZgJGmVah8EOmHDh4wZRSp9JbOPiZ1UAC6LMdHYJ2qs" width="200" height="113" class="media-oembed-content" loading="eager" title="91Թ:"></iframe> </div> </div> <p>&nbsp;</p> <p>“It will be useful when I talk about AI risks,” he says, referring to <a href="https://www.youtube.com/watch?v=-9cW4Gcn5WY">the warning bell he began sounding in 2023</a> about the potential existential threat posed by rapid and unchecked AI development.&nbsp;&nbsp;</p> <p>“It will make people take me more seriously.”&nbsp;</p> <p>For example, he was recently invited to be part of a webinar with Nobel Peace Prize laureates on whether AI should be used to decide if and when to launch nuclear weapons – a foreboding new twist on <a href="/news/prohibition-nuclear-weapons-only-rational-way-forward-john-polanyi-globe-and-mail">a Cold War-era threat that has preoccupied</a> fellow 91Թ Nobel laureate <strong>John Polanyi</strong>, a University Professor emeritus of chemistry.&nbsp;&nbsp;</p> <p>“I think it’s a bad idea,” Hinton says for the record.&nbsp;&nbsp;&nbsp;</p> <p>Yet, as scary as such a scenario is to contemplate, Hinton has focused on what he considers an equally grave threat to humanity: the moment when machine intelligence surpasses that of our own.&nbsp;&nbsp;</p> <p>That’s why he’s called on governments to develop regulations to guide AI development and deployment. It’s also why he’s urging companies to devote more funding to AI safety research as they rush to explore the myriad ways the technology can be used to make our lives better – from finding cures for deadly diseases to discovering new materials to help combat climate change.&nbsp;&nbsp;</p> <p>At 91Թ, Hinton has also taken on an advisory role at the <a href="https://srinstitute.utoronto.ca/">Schwartz Reisman Institute of Technology and Society</a>, where researchers are at the forefront of exploring AI safety and other issues around the adoption of new technologies. In particular, he highlights the work of <strong>Roger Grosse</strong> and <strong>David Duvenaud</strong> – both AI safety experts who are associate professors in the department of computer science in the Faculty of Arts &amp; Science and Schwartz Reisman Chairs in Technology and Society (he says Grosse convinced him to <a href="https://www.theguardian.com/technology/2023/may/02/geoffrey-hinton-godfather-of-ai-quits-google-warns-dangers-of-machine-learning">go public with his concerns last year after he left a senior research position at Google</a>).&nbsp;</p> <p>The institute and 91Թ more broadly have an opportunity to become a world leader in figuring out how to guard against AI threats, he says. “I think that can be a world-class centre for figuring out whether there’s a way to make a superintelligence – which we all think is coming – not want to take control.”&nbsp;&nbsp;&nbsp;</p> <p>Hinton’s moment in the spotlight has been a long time coming – and is testament to his curious mind, persistent nature and willingness to go against the grain.&nbsp;</p> <p>As a child attending a “mildly Christian school” in England, he says he often felt like an outsider because he refused to accept the idea of a god without evidence (he remains an atheist). Decades later, Hinton again found himself on the fringe as he and a handful of researchers, including the Salk Institute for Biological Science’s <strong>Terry Sejnowsky</strong>, who did his PhD research under Hopfield, explored the idea that the human brain was essentially a bunch of connection strengths between neurons – not a series of logical expressions, as many in the field then believed.&nbsp;</p> <p>That key insight now forms the basis of today neural nets.&nbsp;</p> <p>“There were many times when I could easily have given up and sort of joined the mainstream,” Hinton says. “But I think my experience as a child made me far more resistant to that.”&nbsp;</p> <p>A self-described cognitive scientist who works in the field of computer science, Hinton says he was surprised to win a Nobel Prize in Physics. But <a href="https://www.nobelprize.org/prizes/physics/2024/hinton/facts/">the Nobel committee noted</a> he used ideas from physics to create the Boltzmann machine, which can be used to recognize elements in data. The Boltzmann machine, in turn, was based on the Hopfield network, which was invented by his co-laureate.&nbsp;&nbsp;</p> <figure role="group" class="caption caption-drupal-media align-center"> <div> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/styles/scale_image_750_width_/public/2024-12/UofT96534_2024-11-14-Hinton-Boltzmann-%283%29-smaller-crop.jpg?itok=pLbrDC5d" width="750" height="500" alt="&quot;&quot;" class="image-style-scale-image-750-width-"> </div> </div> <figcaption><em>(photo by Johnny Guatto)</em></figcaption> </figure> <p>Hinton is donating an early Boltzmann chip, about the size of a postage stamp, to the Nobel Prize Museum – and has decided to use the money from his win to set up a prize for young researchers at the annual Conference on Neural Information Processing Systems. He has also donated to a Canadian charity that supports works with Indigenous communities to address water challenges, and has plans to give to another that supports neurodiverse young adults.&nbsp;</p> <p>For young researchers hoping to follow in his footsteps? Hinton advises: focus on a problem that really excites you, don’t become swayed by conventional thinking, persevere until you know you’re wrong – and feel free to wander between different research disciplines.&nbsp;&nbsp;</p> <p>“If you're really interested in chasing a criminal, you don't stop at a state border,” he says. “That's a stupid thing to do – so, the boundaries of fields, you just ignore them.”&nbsp;</p> </div> <div class="field field--name-field-news-home-page-banner field--type-boolean field--label-above"> <div class="field__label">News home page banner</div> <div class="field__item">Off</div> </div> Wed, 04 Dec 2024 17:56:55 +0000 lanthierj 310863 at Should you eat soy after menopause? 91Թ researchers dispel myth about soy and cancer /news/should-you-eat-soy-after-menopause-u-t-researchers-dispel-myth-about-soy-and-cancer <span class="field field--name-title field--type-string field--label-hidden">Should you eat soy after menopause? 91Թ researchers dispel myth about soy and cancer</span> <div class="field field--name-field-featured-picture field--type-image field--label-hidden field__item"> <img loading="eager" srcset="/sites/default/files/styles/news_banner_370/public/2024-12/GettyImages-1351412777-crop.jpg?h=81d682ee&amp;itok=2JvXY3iA 370w, /sites/default/files/styles/news_banner_740/public/2024-12/GettyImages-1351412777-crop.jpg?h=81d682ee&amp;itok=bYKNmtR2 740w, /sites/default/files/styles/news_banner_1110/public/2024-12/GettyImages-1351412777-crop.jpg?h=81d682ee&amp;itok=Pcv8Bks6 1110w" sizes="(min-width:1200px) 1110px, (max-width: 1199px) 80vw, (max-width: 767px) 90vw, (max-width: 575px) 95vw" width="740" height="494" src="/sites/default/files/styles/news_banner_370/public/2024-12/GettyImages-1351412777-crop.jpg?h=81d682ee&amp;itok=2JvXY3iA" alt="older asian woman eating a tofu salad"> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span>rahul.kalvapalle</span></span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2024-12-03T19:53:18-05:00" title="Tuesday, December 3, 2024 - 19:53" class="datetime">Tue, 12/03/2024 - 19:53</time> </span> <div class="clearfix text-formatted field field--name-field-cutline-long field--type-text-long field--label-above"> <div class="field__label">Cutline</div> <div class="field__item"><p><em>A study led by researchers at the Temerty Faculty of Medicine's department of nutritional sciences found that soy isoflavones – estrogen-like compounds – had no effect on key markers of estrogen-related cancers (photo by Yagi Studio/Getty Images)</em></p> </div> </div> <div class="field field--name-field-author-reporters field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/news/authors-reporters/betty-zou" hreflang="en">Betty Zou</a></div> </div> <div class="field field--name-field-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__item"><a href="/news/topics/breaking-research" hreflang="en">Breaking Research</a></div> </div> <div class="field field--name-field-story-tags field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/news/tags/temerty-faculty-medicine" hreflang="en">Temerty Faculty of Medicine</a></div> <div class="field__item"><a href="/news/tags/unity-health" hreflang="en">Unity Health</a></div> <div class="field__item"><a href="/news/tags/nutritional-sciences" hreflang="en">Nutritional Sciences</a></div> <div class="field__item"><a href="/news/tags/st-michael-s-hospital" hreflang="en">St. Michael's Hospital</a></div> </div> <div class="field field--name-field-subheadline field--type-string-long field--label-above"> <div class="field__label">Subheadline</div> <div class="field__item">“We hope our study will help people feel more comfortable including soy foods in their diet"</div> </div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>A study led by experts at the 91Թ's Temerty Faculty of Medicine is providing reassuring evidence on consumption of soy foods during postmenopause.</p> <p>In a systematic review and meta-analysis of 40 trials in over 3,000 participants, 91Թ researchers gathered results on the effects of soy isoflavones – estrogen-like compounds naturally found in plants – on biological outcomes related to risk of endometrial and other female-related cancers.</p> <p>Their results, published in&nbsp;<a href="https://www.sciencedirect.com/science/article/pii/S2161831324001613?via%3Dihub"><em>Advances in Nutrition</em></a>, found that isoflavones had no effect on key markers of estrogen-related cancers, supporting the safety of soy as a food as well as potential therapy.</p> <p>“The risk of cardiovascular disease increases substantially as women* go through menopause, so soy can offer dual benefits during this particular phase of life,” says the study’s senior author&nbsp;<strong>Laura Chiavaroli</strong>, an assistant professor in Temerty's department of nutritional sciences and affiliate scientist at the Li Ka Shing Knowledge Institute at St. Michael’s Hospital, Unity Health Toronto.</p> <figure role="group" class="caption caption-drupal-media align-left"> <div> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/2024-12/Chiavaroli_Viscardi-crop.jpg" width="350" height="228" alt="&quot;"> </div> </div> <figcaption><em>Assistant Professor Laura Chiavaroli (left) and PhD student Gabrielle Viscardi (supplied images)</em></figcaption> </figure> <p>Yet, Chiavaroli notes many people are hesitant to eat soy foods because they contain isoflavones, which have a similar structure to estrogen. In animal studies, large doses of isoflavones have been linked to a higher risk of cancer.</p> <p>“Something we hear very often is that people have a lot of concern about consuming soy because there are so many conflicting messages out there,” says&nbsp;<strong>Gabrielle Viscardi</strong>, a second-year PhD student in the department of nutritional sciences and the study’s lead author.</p> <p>This is despite the fact that several health advocacy groups, including the Canadian Cardiovascular Society, already recommend soy foods as part of a healthy diet. Health Canada and the U.S. Food and Drug Administration have both recognized soy&nbsp;– a high-quality and complete source of protein – as effective in reducing the risk of heart disease</p> <p>Soy foods have also been shown to alleviate hot flashes associated with menopause, which affect many women and impact their quality of life.</p> <p>The trials considered for the 91Թ study followed postmenopausal women from around the world who had consumed either soy isoflavones or a non-isoflavone control for at least three months.</p> <p>The researchers concluded that consumption of soy isoflavones did not affect the four key estrogen-related markers, namely: thickness of uterus lining, vaginal maturation index (a measure of estrogen status) and levels of circulating estrogen and follicle-stimulating hormone.</p> <p>Their findings support the idea that soy isoflavones behave differently from human estrogen, particularly when it comes to cancers that depend on estrogen to develop. “We have estrogen receptors throughout our bodies but, contrary to the hormone estrogen, isoflavones from soy don’t bind to all the estrogen receptors equally,” says Viscardi, who is also a registered dietitian. “That’s why we see a beneficial effect on the cardiovascular system and no effect on the female reproductive system.”</p> <p>This difference in biological activity explains why soy isoflavones have been considered as a possible alternative to hormone replacement therapy (HRT), which is used to treat menopause symptoms by replacing the estrogen that the body stops producing during this period.</p> <p>Chiavaroli notes some people don’t want to take HRTs and are seeking alternative options.</p> <p>Further, HRTs may also not be a good option for people at an increased risk of estrogen-sensitive cancers like breast cancer, as well as those with a history of heart disease and stroke. For these individuals, consuming soy foods as part of a balanced diet could help manage their menopausal symptoms while also reducing the risk of cardiovascular disease.</p> <p>Chiavaroli says the study's findings also align with Health Canada’s dietary guidelines that encourage people to choose plant-based proteins more often, a move that would also convey benefits for the environment.</p> <p>“We hope our study will help people feel more comfortable including soy foods in their diet without being concerned that it’s going to increase their risk of estrogen-dependent cancer,” says Chiavaroli.</p> <p>The study was funded by the United Soybean Board (U.S. Department of Agriculture) and the Canadian Institutes of Health Research through the Canada-wide Human Nutrition Trialists’ Network.</p> <p><em>* Although menopause is sex-specific, the study retains use of the term "women" as it is used conventionally in studies and guidelines on menopause</em></p> </div> <div class="field field--name-field-news-home-page-banner field--type-boolean field--label-above"> <div class="field__label">News home page banner</div> <div class="field__item">Off</div> </div> Wed, 04 Dec 2024 00:53:18 +0000 rahul.kalvapalle 310855 at PhD student's radiopharmaceutical to play key role in clinical trial for lung cancer treatment /news/phd-student-s-radiopharmaceutical-play-key-role-clinical-trial-lung-cancer-treatment <span class="field field--name-title field--type-string field--label-hidden">PhD student's radiopharmaceutical to play key role in clinical trial for lung cancer treatment</span> <div class="field field--name-field-featured-picture field--type-image field--label-hidden field__item"> <img loading="eager" srcset="/sites/default/files/styles/news_banner_370/public/2024-11/stephanie_borlase_faculty-crop.jpg?h=81d682ee&amp;itok=Ws9Kd8ze 370w, /sites/default/files/styles/news_banner_740/public/2024-11/stephanie_borlase_faculty-crop.jpg?h=81d682ee&amp;itok=uVQxg2x8 740w, /sites/default/files/styles/news_banner_1110/public/2024-11/stephanie_borlase_faculty-crop.jpg?h=81d682ee&amp;itok=5HYMeDWJ 1110w" sizes="(min-width:1200px) 1110px, (max-width: 1199px) 80vw, (max-width: 767px) 90vw, (max-width: 575px) 95vw" width="740" height="494" src="/sites/default/files/styles/news_banner_370/public/2024-11/stephanie_borlase_faculty-crop.jpg?h=81d682ee&amp;itok=Ws9Kd8ze" alt="&quot;&quot;"> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span>rahul.kalvapalle</span></span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2024-11-26T15:59:25-05:00" title="Tuesday, November 26, 2024 - 15:59" class="datetime">Tue, 11/26/2024 - 15:59</time> </span> <div class="clearfix text-formatted field field--name-field-cutline-long field--type-text-long field--label-above"> <div class="field__label">Cutline</div> <div class="field__item"><p><em>Stephanie Borlase developed a radiopharmaceutical, which will be used during a clinical trial at Sunnybrook Health Sciences Centre, to track delivery of immunotherapy drugs across the blood-brain barrier (photo by Dana Thompson)</em></p> </div> </div> <div class="field field--name-field-author-reporters field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/news/authors-reporters/eileen-hoftyzer" hreflang="en">Eileen Hoftyzer</a></div> </div> <div class="field field--name-field-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__item"><a href="/news/topics/breaking-research" hreflang="en">Breaking Research</a></div> </div> <div class="field field--name-field-story-tags field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/taxonomy/term/6923" hreflang="en">Sunnybrook Health Sciences Centre</a></div> <div class="field__item"><a href="/news/tags/graduate-students" hreflang="en">Graduate Students</a></div> <div class="field__item"><a href="/news/tags/leslie-dan-faculty-pharmacy" hreflang="en">Leslie Dan Faculty of Pharmacy</a></div> </div> <div class="field field--name-field-subheadline field--type-string-long field--label-above"> <div class="field__label">Subheadline</div> <div class="field__item">The compound developed by 91Թ's Stephanie Borlase will be used to track delivery of immunotherapy drugs to metastases in the brain </div> </div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>A radiopharmaceutical developed by 91Թ PhD student <strong>Stephanie Borlase</strong> is poised to play a key role in a clinical trial that could inform improvements to lung cancer treatment.</p> <p>The trial at Sunnybrook Health Sciences Centre, planned for 2025, will test whether ultrasound can disrupt the blood-brain barrier and increase uptake of immunotherapy into brain metastases – tumours caused by cancer cells spreading to the brain from elsewhere in the body.</p> <p>Although immunotherapy has shown potential as a treatment for lung cancer, it is not able to cross the blood-brain barrier. Borlase’s radiopharmaceutical, which she developed as part of her doctoral research at the Leslie Dan Faculty of Pharmacy, will be used to track delivery of immunotherapy drugs to brain metastases with a PET (positron emission tomography) scan.</p> <p>“This project provides me with the opportunity to learn different aspects of research and be on the forefront of patient treatments,” says Borlase. “It is such an amazing opportunity to be able to see what is happening in the hospital with current patients and clinical trials and know that my research is actually getting to patients.”</p> <p>Borlase completed her undergraduate and master’s degrees at the University of Manitoba, before seeking out a PhD program where she could conduct research that could potentially be translated into therapies for patients with hard-to-treat cancers.</p> <p>In 2022, she began her PhD with Professor <strong>Raymond Reilly</strong>, director of the <a href="https://www.pharmacy.utoronto.ca/research/centres-initiatives/centre-pharmaceutical-oncology">Centre for Pharmaceutical Oncology</a> (CPO), whose research focuses on developing radiopharmaceuticals to image and treat cancer.</p> <p>By attaching radioactive isotopes to highly targeted agents, radiopharmaceuticals allow clinicians to image tumours through scans and deliver therapeutic doses of radiation directly to the tumour.</p> <p>Borlase has been working towards pairing the immunotherapy drug pembrolizumab (also known by the brand name Keytruda) with a radioactive isotope that can be imaged by PET – resulting in a radiopharmaceutical that could allow physicians to determine whether the therapy enters the brain and concentrates better in tumours after the application of focused ultrasound.</p> <p>For the first two years of her PhD, Borlase worked in the CPO’s Good Manufacturing Practices facility to prepare the new radiopharmaceutical for clinical trials, optimizing and formulating the drug in a quality suitable for use in humans, and testing it in pre-clinical models.</p> <p>Reilly says that this is an exceptional experience for a graduate student. “One of the greatest impacts and rewards of pharmaceutical sciences research is to see your work advanced to a clinical trial to make a difference in patient outcomes, which Stephanie has this wonderful opportunity to do,” he says.</p> <p>“Not only is she developing the radiopharmaceutical, but she will be working closely with the oncologists and imaging specialists to design and conduct the trial and will get first-hand experience in seeing the results of her PhD research in the PET images of the patients in the trial.”</p> <p>The trial follows on the heels of another study in which clinicians and scientists at Sunnybrook used a radiopharmaceutical provided by Reilly’s team to track the delivery of a breast cancer drug to brain metastases, resulting in the first evidence that the technique improved uptake of the drug.</p> <p>For her part, Borlase says she hopes the trial will lead to better therapies for a form of cancer that is notoriously difficult to treat.</p> <p>“I always hope that researchers can develop new treatments for cancer because it is such a terrible disease that is never going to disappear. Even if we cannot completely cure the brain metastases, we can work to prolong survival to give these individuals more time with their families and friends,” says Borlase, who recently received a Research Training Award from the Canadian Cancer Society and Brain Canada Foundation.</p> <p>“It's such a rare opportunity for PhD students to be able to work with clinician-scientists or oncologists and actually see their research translate into a clinical setting, so the fact that I am able to do this is incredible.”</p> </div> <div class="field field--name-field-news-home-page-banner field--type-boolean field--label-above"> <div class="field__label">News home page banner</div> <div class="field__item">Off</div> </div> Tue, 26 Nov 2024 20:59:25 +0000 rahul.kalvapalle 310694 at